Slc38a10 solute carrier family 38, member 10 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Slc38a10provided by RGD
Official Full Name: solute carrier family 38, member 10provided by RGD
Primary source: RGD:1306356
See related: EnsemblRapid:ENSRNOG00000004604 AllianceGenome:RGD:1306356
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1306356
Summary: Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to act upstream of or within bone development. Predicted to be located in Golgi apparatus. Predicted to be active in membrane. Orthologous to human SLC38A10 (solute carrier family 38 member 10). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Kidney (RPKM 166.5), Lung (RPKM 163.4) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 10q32.3

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (105885250..105935043, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (105386836..105436636, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (109284054..109333907, complement)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

we have shown that SNAT10 expression is found in most neurons of the mouse brain. It has a unique intracellular localization in several cell lines, strongly suggesting expression in the Golgi. Silencing the expression of SNAT10 in PC12 cells resulted in the reduction of nascent protein synthesis, suggesting that SNAT10 might function as a transceptor.
Title: SLC38A10 (SNAT10) is Located in ER and Golgi Compartments and Has a Role in Regulating Nascent Protein Synthesis.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables L-amino acid transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables active monoatomic ion transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables inorganic cation transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables monoatomic cation transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables neutral L-amino acid transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables secondary active transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in L-alpha-amino acid transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in amino acid transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in bone development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within bone development	ISO Inferred from Sequence Orthology more info
involved_in inorganic cation transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in monoatomic cation transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in neutral amino acid transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi apparatus	ISO Inferred from Sequence Orthology more info
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: solute carrier family 38 member 10

Names: amino acid transporter SLC38A10; putative sodium-coupled neutral amino acid transporter 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001376915.1 → NP_001363844.1 solute carrier family 38 member 10

Status: VALIDATED

Source sequence(s)

JAXUCZ010000010

UniProtKB/TrEMBL

A0A8I5ZRR0, A0A8L2Q2J1

Related

ENSRNOP00000006225.7, ENSRNOT00000006225.10

Conserved Domains (2) summary

PTZ00121
Location:396 → 1076

PTZ00121; MAEBL; Provisional

cl00456
Location:6 → 381

SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086028.1 Reference GRCr8

Range

105885250..105935043 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_221195.10 → XP_221195.5 solute carrier family 38 member 10 isoform X5

See identical proteins and their annotated locations for XP_221195.5

UniProtKB/Swiss-Prot

E9PT23

UniProtKB/TrEMBL

A0A8I5ZRR0

Conserved Domains (2) summary

COG0814
Location:3 → 398

SdaC; Amino acid permease [Amino acid transport and metabolism]

cl00456
Location:6 → 381

SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
XM_063269250.1 → XP_063125320.1 solute carrier family 38 member 10 isoform X12

UniProtKB/TrEMBL

A0A8I5ZRR0

Related

ENSRNOP00000081337.2, ENSRNOT00000095802.2
XM_039086218.2 → XP_038942146.1 solute carrier family 38 member 10 isoform X11

UniProtKB/TrEMBL

A0A8I5ZRR0

Conserved Domains (2) summary

PTZ00121
Location:335 → 1016

PTZ00121; MAEBL; Provisional

cl00456
Location:6 → 320

SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
XM_039086217.2 → XP_038942145.1 solute carrier family 38 member 10 isoform X10

UniProtKB/TrEMBL

A6HLB3

Conserved Domains (2) summary

PTZ00121
Location:335 → 1024

PTZ00121; MAEBL; Provisional

cl00456
Location:6 → 320

SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
XM_063269248.1 → XP_063125318.1 solute carrier family 38 member 10 isoform X7

UniProtKB/TrEMBL

A0A8I5ZRR0
XM_006247946.4 → XP_006248008.1 solute carrier family 38 member 10 isoform X6

See identical proteins and their annotated locations for XP_006248008.1

UniProtKB/TrEMBL

A0A8I5ZRR0

Conserved Domains (2) summary

COG0814
Location:3 → 398

SdaC; Amino acid permease [Amino acid transport and metabolism]

cl00456
Location:6 → 381

SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
XM_039086215.2 → XP_038942143.1 solute carrier family 38 member 10 isoform X4

UniProtKB/TrEMBL

A6HLB3

Conserved Domains (2) summary

PTZ00121
Location:396 → 1028

PTZ00121; MAEBL; Provisional

cl00456
Location:6 → 381

SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
XM_006247943.4 → XP_006248005.1 solute carrier family 38 member 10 isoform X2

See identical proteins and their annotated locations for XP_006248005.1

UniProtKB/TrEMBL

A6HLB3

Conserved Domains (2) summary

COG0814
Location:3 → 398

SdaC; Amino acid permease [Amino acid transport and metabolism]

cl00456
Location:6 → 381

SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
XM_006247944.5 → XP_006248006.1 solute carrier family 38 member 10 isoform X3

See identical proteins and their annotated locations for XP_006248006.1

UniProtKB/TrEMBL

A0A8I6A7H4, A6HLB3

Related

ENSRNOP00000086955.1, ENSRNOT00000094909.2

Conserved Domains (2) summary

COG0814
Location:3 → 398

SdaC; Amino acid permease [Amino acid transport and metabolism]

cl00456
Location:6 → 381

SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
XM_002727846.6 → XP_002727892.2 solute carrier family 38 member 10 isoform X1

See identical proteins and their annotated locations for XP_002727892.2

UniProtKB/TrEMBL

A6HLB3

Conserved Domains (2) summary

COG0814
Location:3 → 398

SdaC; Amino acid permease [Amino acid transport and metabolism]

cl00456
Location:6 → 381

SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
XM_063269249.1 → XP_063125319.1 solute carrier family 38 member 10 isoform X9

UniProtKB/TrEMBL

A0A8I5ZRR0
XM_039086216.2 → XP_038942144.1 solute carrier family 38 member 10 isoform X8

UniProtKB/TrEMBL

A6HLB3

Conserved Domains (2) summary

PTZ00121
Location:348 → 1037

PTZ00121; MAEBL; Provisional

cl00456
Location:17 → 333

SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
XM_039086219.2 → XP_038942147.1 solute carrier family 38 member 10 isoform X13

UniProtKB/TrEMBL

A6HLB3

Conserved Domains (2) summary

PTZ00121
Location:251 → 940

PTZ00121; MAEBL; Provisional

cl00456
Location:2 → 236

SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
XM_039086220.2 → XP_038942148.1 solute carrier family 38 member 10 isoform X14

Conserved Domains (2) summary

PTZ00121
Location:146 → 508

PTZ00121; MAEBL; Provisional

cl00456
Location:2 → 110

SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain