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    Lin37 lin-37 DREAM MuvB core complex component [ Rattus norvegicus (Norway rat) ]

    Gene ID: 292787, updated on 9-Dec-2024

    Summary

    Official Symbol
    Lin37provided by RGD
    Official Full Name
    lin-37 DREAM MuvB core complex componentprovided by RGD
    Primary source
    RGD:1308901
    See related
    EnsemblRapid:ENSRNOG00000020929 AllianceGenome:RGD:1308901
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1308901
    Summary
    Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be part of Myb complex. Orthologous to human LIN37 (lin-37 DREAM MuvB core complex component). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 601.3), Muscle (RPKM 540.7) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Lin37 in Genome Data Viewer
    Location:
    1q21
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (94936512..94940444, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (85809065..85813235, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (89010254..89014481, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120097050 Neighboring gene proline and serine rich 3 Neighboring gene heat shock protein family B (small) member 6 Neighboring gene presenilin enhancer gamma secretase subunit Neighboring gene U2 small nuclear RNA auxiliary factor 1-like 4 Neighboring gene IGF-like family receptor 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of Myb complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of transcription repressor complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein lin-37 homolog
    Names
    lin-37 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106245.1NP_001099715.1  protein lin-37 homolog

      See identical proteins and their annotated locations for NP_001099715.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473979
      UniProtKB/TrEMBL
      A6J9Y6, D4A503
      Related
      ENSRNOP00000028413.6, ENSRNOT00000028413.7
      Conserved Domains (1) summary
      pfam15306
      Location:84240
      LIN37

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      94936512..94940444 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)