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    Zfp213 zinc finger protein 213 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287094, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp213provided by RGD
    Official Full Name
    zinc finger protein 213provided by RGD
    Primary source
    RGD:1305919
    See related
    EnsemblRapid:ENSRNOG00000021872 AllianceGenome:RGD:1305919
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Znf213
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZNF213 (zinc finger protein 213). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 40.9), Kidney (RPKM 37.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfp213 in Genome Data Viewer
    Location:
    10q12
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (13096995..13103918, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (12592368..12599296, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (12885533..12892464, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene caspase 16 Neighboring gene transfer RNA arginine (anticodon CCU) 4 Neighboring gene transfer RNA arginine (anticodon CCG) 1 Neighboring gene uncharacterized LOC120095040 Neighboring gene zinc finger protein 13

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 213

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105764.1 → NP_001099234.1  zinc finger protein 213

      See identical proteins and their annotated locations for NP_001099234.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473948
      UniProtKB/TrEMBL
      A6HCJ4, D4A1V0
      Related
      ENSRNOP00000038605.4, ENSRNOT00000030704.6
      Conserved Domains (6) summary
      smart00431
      Location:41 → 140
      SCAN; leucine rich region
      COG5048
      Location:245 → 381
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:249 → 269
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:331 → 353
      zf-C2H2; Zinc finger, C2H2 type
      pfam02023
      Location:41 → 124
      SCAN; SCAN domain
      pfam13465
      Location:261 → 286
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      13096995..13103918 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039085343.2 → XP_038941271.1  zinc finger protein 213 isoform X5

      UniProtKB/TrEMBL
      A6HCJ6
      Conserved Domains (1) summary
      cl02605
      Location:41 → 140
      SCAN; SCAN oligomerization domain

    2. XM_006245862.5 → XP_006245924.1  zinc finger protein 213 isoform X1

      See identical proteins and their annotated locations for XP_006245924.1

      UniProtKB/TrEMBL
      A0A8I6ADN5
      Related
      ENSRNOP00000092440.1, ENSRNOT00000104194.2
      Conserved Domains (7) summary
      smart00431
      Location:41 → 140
      SCAN; leucine rich region
      cd07765
      Location:213 → 247
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
      COG5048
      Location:324 → 460
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:328 → 348
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:410 → 432
      zf-C2H2; Zinc finger, C2H2 type
      pfam02023
      Location:41 → 124
      SCAN; SCAN domain
      pfam13465
      Location:340 → 365
      zf-H2C2_2; Zinc-finger double domain

    3. XM_006245863.3 → XP_006245925.1  zinc finger protein 213 isoform X1

      See identical proteins and their annotated locations for XP_006245925.1

      UniProtKB/TrEMBL
      A0A8I6ADN5
      Conserved Domains (7) summary
      smart00431
      Location:41 → 140
      SCAN; leucine rich region
      cd07765
      Location:213 → 247
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
      COG5048
      Location:324 → 460
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:328 → 348
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:410 → 432
      zf-C2H2; Zinc finger, C2H2 type
      pfam02023
      Location:41 → 124
      SCAN; SCAN domain
      pfam13465
      Location:340 → 365
      zf-H2C2_2; Zinc-finger double domain

    4. XM_063268537.1 → XP_063124607.1  zinc finger protein 213 isoform X5

      UniProtKB/TrEMBL
      A6HCJ6

    5. XM_039085340.1 → XP_038941268.1  zinc finger protein 213 isoform X3

      UniProtKB/TrEMBL
      A6HCJ5
      Conserved Domains (3) summary
      cd07765
      Location:28 → 62
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
      COG5048
      Location:139 → 275
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:143 → 163
      ZF_C2H2; C2H2 Zn finger [structural motif]

    6. XM_039085342.2 → XP_038941270.1  zinc finger protein 213 isoform X4

      UniProtKB/TrEMBL
      A6HCJ6
      Conserved Domains (1) summary
      cl02605
      Location:41 → 140
      SCAN; SCAN oligomerization domain

    7. XM_039085339.2 → XP_038941267.1  zinc finger protein 213 isoform X2

      Conserved Domains (2) summary
      cd07765
      Location:213 → 247
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
      cl02605
      Location:41 → 140
      SCAN; SCAN oligomerization domain

    8. XM_063268535.1 → XP_063124605.1  zinc finger protein 213 isoform X4

      UniProtKB/TrEMBL
      A6HCJ6
    Nucleotide Protein Strain
    Heading Accession and Version

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