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    Zfp455l1 zinc finger protein 455 like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 680200, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp455l1provided by RGD
    Official Full Name
    zinc finger protein 455 like 1provided by RGD
    Primary source
    RGD:1594231
    See related
    EnsemblRapid:ENSRNOG00000042308 AllianceGenome:RGD:1594231
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF429 (zinc finger protein 429). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 73.1), Thymus (RPKM 58.4) and 9 other tissues See more
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    Genomic context

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    See Zfp455l1 in Genome Data Viewer
    Location:
    1p11
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (36755197..36773283, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (34866934..34944939, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (37802591..37818879, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene FAST kinase domains 3 Neighboring gene 5-methyltetrahydrofolate-homocysteine methyltransferase reductase Neighboring gene uncharacterized LOC134482589 Neighboring gene zinc finger protein 726 like, pseudogene 1 Neighboring gene U7 small nuclear RNA Neighboring gene protein NYNRIN-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC189378

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 455 like 1
    Names
    zinc finger protein 455-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001139491.2 → NP_001132963.1  zinc finger protein 455 like 1 isoform 2

      See identical proteins and their annotated locations for NP_001132963.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      B2RZ85
      Conserved Domains (4) summary
      smart00349
      Location:2 → 61
      KRAB; krueppel associated box
      COG5048
      Location:131 → 424
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:360 → 380
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd20908
      Location:104 → 152
      SUF4-like; N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins

    2. NM_001419516.1 → NP_001406445.1  zinc finger protein 455 like 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      B2RZ85

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      36755197..36773283 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063273570.1 → XP_063129640.1  zinc finger protein 455 like 1 isoform X1

      UniProtKB/TrEMBL
      B2RZ85

    2. XM_063273566.1 → XP_063129636.1  zinc finger protein 455 like 1 isoform X1

      UniProtKB/TrEMBL
      B2RZ85

    3. XM_063273561.1 → XP_063129631.1  zinc finger protein 455 like 1 isoform X1

      UniProtKB/TrEMBL
      B2RZ85
      Related
      ENSRNOP00000049291.3, ENSRNOT00000043747.6
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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