Naa40 N(alpha)-acetyltransferase 40, NatD catalytic subunit [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Naa40provided by RGD
Official Full Name: N(alpha)-acetyltransferase 40, NatD catalytic subunitprovided by RGD
Primary source: RGD:1565838
See related: EnsemblRapid:ENSRNOG00000021179 AllianceGenome:RGD:1565838
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Nat11; RGD1565838
Summary: Predicted to enable histone H2A acetyltransferase activity; histone H4 acetyltransferase activity; and peptide-serine-alpha-N-acetyltransferase activity. Predicted to be involved in chromatin remodeling. Predicted to act upstream of or within lipid metabolic process. Predicted to be located in centriolar satellite; cytosol; and nucleoplasm. Predicted to be active in nucleus. Orthologous to human NAA40 (N-alpha-acetyltransferase 40, NatD catalytic subunit). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Heart (RPKM 70.9), Thymus (RPKM 59.0) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1q43

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (213842686..213860079, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (204410636..204430890, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (222478021..222495382, complement)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

UniSTS:479130 (e-PCR)
- UniSTS:479130

Hnrpr (e-PCR), detects polymorphism
- UniSTS:479130

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables histone H2A acetyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables histone H2A acetyltransferase activity	ISO Inferred from Sequence Orthology more info
enables histone H4 acetyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables histone H4 acetyltransferase activity	ISO Inferred from Sequence Orthology more info
enables peptide-serine-alpha-N-acetyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables peptide-serine-alpha-N-acetyltransferase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in chromatin remodeling	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within lipid metabolic process	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in centriolar satellite	IEA Inferred from Electronic Annotation more info
located_in centriolar satellite	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: N-alpha-acetyltransferase 40

Names: N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog; N-acetyltransferase 11

NP_001101988.1

EC 2.3.1.-

XP_038940000.1

EC 2.3.1.-

XP_038940010.1

EC 2.3.1.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001108518.1 → NP_001101988.1 N-alpha-acetyltransferase 40

See identical proteins and their annotated locations for NP_001101988.1

Status: PROVISIONAL

Source sequence(s)

CH473953

UniProtKB/TrEMBL

A6HZP0, D3ZZQ5

Related

ENSRNOP00000028759.4, ENSRNOT00000028759.7

Conserved Domains (1) summary

pfam00583
Location:80 → 188

Acetyltransf_1; Acetyltransferase (GNAT) family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086019.1 Reference GRCr8

Range

213842686..213860079 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039084082.2 → XP_038940010.1 N-alpha-acetyltransferase 40 isoform X2

UniProtKB/TrEMBL

A0A8I6A7S4
XM_039084072.2 → XP_038940000.1 N-alpha-acetyltransferase 40 isoform X1

Conserved Domains (1) summary

pfam00583
Location:94 → 135

Acetyltransf_1; Acetyltransferase (GNAT) family