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    Apol11a apolipoprotein L11a [ Rattus norvegicus (Norway rat) ]

    Gene ID: 300060, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Apol11aprovided by RGD
    Official Full Name
    apolipoprotein L11aprovided by RGD
    Primary source
    RGD:1309798
    See related
    AllianceGenome:RGD:1309798
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309798; Apol11a-ps1
    Summary
    Predicted to enable lipid binding activity. Predicted to be involved in lipid transport and lipoprotein metabolic process. Predicted to be located in extracellular region. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human APOL1 (apolipoprotein L1) and APOL2 (apolipoprotein L2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 104.5), Heart (RPKM 99.5) and 8 other tissues See more
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    Genomic context

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    See Apol11a in Genome Data Viewer
    Location:
    7q34
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (111118668..111142866, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (109248260..109262266, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (118835316..118858347, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120093820 Neighboring gene DNA polymerase epsilon 3, accessory subunit, pseudogene 3 Neighboring gene uncharacterized LOC134479936 Neighboring gene uncharacterized LOC102552424 Neighboring gene apolipoprotein L3 like 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables lipid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in lipid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in lipoprotein metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    apolipoprotein L3-like
    Names
    apolipoprotein L 11a, pseudogene 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      111118668..111142866 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006241949.5 → XP_006242011.1  apolipoprotein L3-like isoform X1

      See identical proteins and their annotated locations for XP_006242011.1

      Conserved Domains (1) summary
      pfam05461
      Location:162 → 456
      ApoL; Apolipoprotein L

    2. XM_008765647.4 → XP_008763869.1  apolipoprotein L3-like isoform X2

      See identical proteins and their annotated locations for XP_008763869.1

      UniProtKB/TrEMBL
      F1M512
      Conserved Domains (1) summary
      pfam05461
      Location:42 → 336
      ApoL; Apolipoprotein L
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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