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    Ms4a6a membrane spanning 4-domains A6A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361735, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ms4a6aprovided by RGD
    Official Full Name
    membrane spanning 4-domains A6Aprovided by RGD
    Primary source
    RGD:1305800
    See related
    EnsemblRapid:ENSRNOG00000020991 AllianceGenome:RGD:1305800
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ms4a11
    Summary
    Predicted to be involved in cell surface receptor signaling pathway. Predicted to be active in plasma membrane and trans-Golgi network. Orthologous to human MS4A6A (membrane spanning 4-domains A6A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 160.7), Liver (RPKM 64.4) and 7 other tissues See more
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    Genomic context

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    See Ms4a6a in Genome Data Viewer
    Location:
    1q43
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (217826261..217839606, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (208401465..208414831, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (227919284..227932637, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102551452 Neighboring gene membrane-spanning 4-domains, subfamily A, member 4C, pseudogene 1 Neighboring gene membrane-spanning 4-domains, subfamily A, member 6B-like 2 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene membrane spanning 4-domains A2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in cell surface receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in trans-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in trans-Golgi network ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    membrane-spanning 4-domains subfamily A member 6D
    Names
    membrane-spanning 4-domains, subfamily A, member 11
    membrane-spanning 4-domains, subfamily A, member 6A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001408758.1 → NP_001395687.1  membrane-spanning 4-domains subfamily A member 6D

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A6I099, F1LZT4
      Related
      ENSRNOP00000034434.7, ENSRNOT00000033795.8

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      217826261..217839606 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039101356.2 → XP_038957284.1  membrane-spanning 4-domains subfamily A member 6D isoform X2

      Conserved Domains (1) summary
      pfam04103
      Location:1 → 156
      CD20; CD20-like family

    2. XM_039101355.2 → XP_038957283.1  membrane-spanning 4-domains subfamily A member 6D isoform X1

      UniProtKB/TrEMBL
      A6I099, F1LZT4
      Conserved Domains (1) summary
      pfam04103
      Location:47 → 209
      CD20; CD20-like family
    Nucleotide Protein Strain
    Heading Accession and Version

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