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    Barhl2 BarH-like homeobox 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 65050, updated on 9-Dec-2024

    Summary

    Official Symbol
    Barhl2provided by RGD
    Official Full Name
    BarH-like homeobox 2provided by RGD
    Primary source
    RGD:620726
    See related
    EnsemblRapid:ENSRNOG00000002117 AllianceGenome:RGD:620726
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Barh; MBH1
    Summary
    Enables DNA-binding transcription factor activity. Involved in nervous system development and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in oral squamous cell carcinoma. Orthologous to human BARHL2 (BarH like homeobox 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 19.3) See more
    Orthologs
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    Genomic context

    See Barhl2 in Genome Data Viewer
    Location:
    14p22
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (3485309..3490206)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (3340465..3345362)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (4362717..4367614)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene keratin-associated protein 10-6-like Neighboring gene basic salivary proline-rich protein 2-like Neighboring gene uncharacterized LOC134481697 Neighboring gene uncharacterized LOC102551594

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in nucleus  
    located_in nucleus  

    General protein information

    Preferred Names
    barH-like 2 homeobox protein
    Names
    BarH-class homeodomain transcription factor
    bar-class homeodomain protein MBH1
    homeobox protein B-H1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_022956.2NP_075245.1  barH-like 2 homeobox protein

      See identical proteins and their annotated locations for NP_075245.1

      Status: PROVISIONAL

      Source sequence(s)
      AB004056
      UniProtKB/Swiss-Prot
      O88181
      UniProtKB/TrEMBL
      A6KPL6
      Related
      ENSRNOP00000002887.2, ENSRNOT00000002887.5
      Conserved Domains (1) summary
      pfam00046
      Location:233285
      Homeobox; Homeobox domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      3485309..3490206
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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