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    Acyp1 acylphosphatase 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 299203, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Acyp1provided by RGD
    Official Full Name
    acylphosphatase 1provided by RGD
    Primary source
    RGD:1311327
    See related
    EnsemblRapid:ENSRNOG00000006744 AllianceGenome:RGD:1311327
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable acylphosphatase activity. Orthologous to human ACYP1 (acylphosphatase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 215.0), Thymus (RPKM 163.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Acyp1 in Genome Data Viewer
    Location:
    6q31
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (110650213..110663404, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (104919162..104932348, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (109097065..109110266, complement)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 2B subunit beta Neighboring gene mutL homolog 3 Neighboring gene zinc finger, C2HC-type containing 1C Neighboring gene NIMA-related kinase 9

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, et al. J Proteome Res, 2012 Sep 7. PMID 22871113, Free PMC Article
    2. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables acylphosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    acylphosphatase-1
    Names
    acylphosphatase 1, erythrocyte (common) type
    NP_001100216.1
    NP_001186096.1
    NP_001186097.1
    XP_006240370.1
    XP_017449587.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106746.2 → NP_001100216.1  acylphosphatase-1

      See identical proteins and their annotated locations for NP_001100216.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      FM062949, JAXUCZ010000006
      UniProtKB/TrEMBL
      A6JE20, D4A6X4
      Related
      ENSRNOP00000009086.5, ENSRNOT00000009086.8
      Conserved Domains (1) summary
      pfam00708
      Location:10 → 97
      Acylphosphatase

    2. NM_001199167.1 → NP_001186096.1  acylphosphatase-1

      See identical proteins and their annotated locations for NP_001186096.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      A6JE20, D4A6X4
      Conserved Domains (1) summary
      pfam00708
      Location:10 → 97
      Acylphosphatase

    3. NM_001199168.1 → NP_001186097.1  acylphosphatase-1

      See identical proteins and their annotated locations for NP_001186097.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      FM034312, JAXUCZ010000006
      UniProtKB/TrEMBL
      A6JE20, D4A6X4
      Conserved Domains (1) summary
      pfam00708
      Location:10 → 97
      Acylphosphatase

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      110650213..110663404 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017594098.3 → XP_017449587.1  acylphosphatase-1 isoform X1

      UniProtKB/TrEMBL
      A0A0G2K899

    2. XM_006240308.5 → XP_006240370.1  acylphosphatase-1 isoform X2

      See identical proteins and their annotated locations for XP_006240370.1

      UniProtKB/TrEMBL
      A6JE20, D4A6X4
      Conserved Domains (1) summary
      pfam00708
      Location:10 → 97
      Acylphosphatase
    Nucleotide Protein Strain
    Heading Accession and Version

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