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    Zfp853 zinc finger protein 853 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 102555274, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp853provided by RGD
    Official Full Name
    zinc finger protein 853provided by RGD
    Primary source
    RGD:1563095
    See related
    AllianceGenome:RGD:1563095
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1563095
    Summary
    Predicted to be located in nucleus. Orthologous to human ZNF853 (zinc finger protein 853). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 14.5), Lung (RPKM 10.7) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfp853 in Genome Data Viewer
    Location:
    12p11
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (16379552..16390082)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (11266124..11276492)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (13323102..13331353)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene zinc finger DHHC-type palmitoyltransferase 4 Neighboring gene integrator complex subunit 15 Neighboring gene uncharacterized LOC108352423 Neighboring gene zinc finger protein 316 Neighboring gene zinc finger protein 12

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 853

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      16379552..16390082
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039089853.2 → XP_038945781.1  zinc finger protein 853 isoform X1

      Conserved Domains (2) summary
      COG5048
      Location:690 → 805
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:721 → 741
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_039089854.2 → XP_038945782.1  zinc finger protein 853 isoform X2

      UniProtKB/TrEMBL
      M0RAV1
      Conserved Domains (4) summary
      COG5048
      Location:552 → 605
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:556 → 576
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:610 → 632
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:596 → 620
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein Strain
    Heading Accession and Version

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