Zcchc3 zinc finger CCHC-type containing 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Zcchc3provided by RGD
Full Name: zinc finger CCHC-type containing 3provided by RGD
Primary source: RGD:1585203
See related: EnsemblRapid:ENSRNOG00000068900 AllianceGenome:RGD:1585203
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable double-stranded DNA binding activity. Predicted to be involved in several processes, including cellular response to exogenous dsRNA; positive regulation of innate immune response; and response to virus. Predicted to be active in cytoplasm. Orthologous to human ZCCHC3 (zinc finger CCHC-type containing 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: 3q41

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (161332760..161335591, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (140872460..140875292, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (147877321..147881434, complement)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables double-stranded DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables double-stranded DNA binding	ISO Inferred from Sequence Orthology more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in activation of innate immune response	IBA Inferred from Biological aspect of Ancestor more info
involved_in activation of innate immune response	ISO Inferred from Sequence Orthology more info
involved_in cellular response to exogenous dsRNA	IBA Inferred from Biological aspect of Ancestor more info
involved_in cellular response to exogenous dsRNA	ISO Inferred from Sequence Orthology more info
involved_in defense response to virus	IBA Inferred from Biological aspect of Ancestor more info
involved_in defense response to virus	ISO Inferred from Sequence Orthology more info
involved_in detection of virus	IBA Inferred from Biological aspect of Ancestor more info
involved_in detection of virus	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of RIG-I signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of RIG-I signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of type I interferon production	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of type I interferon production	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: zinc finger CCHC domain-containing protein 3

Names: zinc finger, CCHC domain containing 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.