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    Tpd52l1 TPD52 like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 689256, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tpd52l1provided by RGD
    Official Full Name
    TPD52 like 1provided by RGD
    Primary source
    RGD:1594796
    See related
    EnsemblRapid:ENSRNOG00000021478 AllianceGenome:RGD:1594796
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable protein homodimerization activity. Predicted to be involved in G2/M transition of mitotic cell cycle and positive regulation of signal transduction. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in cytoplasm. Orthologous to human TPD52L1 (TPD52 like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 72.0), Heart (RPKM 66.5) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Tpd52l1 in Genome Data Viewer
    Location:
    1p11
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (27991114..28109767)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (26172038..26290704)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (28454949..28578736)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene ring finger protein 217 Neighboring gene uncharacterized LOC134484976 Neighboring gene HD domain containing 2 Neighboring gene uncharacterized LOC134484854 Neighboring gene SEC24 homolog C, COPII coat complex component, pseudogene 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in cytoplasm  
    located_in cytoplasm  
    located_in perinuclear region of cytoplasm  

    General protein information

    Preferred Names
    tumor protein D53
    Names
    tumor protein D52-like 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044295.1NP_001037760.1  tumor protein D53

      See identical proteins and their annotated locations for NP_001037760.1

      Status: PROVISIONAL

      Source sequence(s)
      BC099809
      UniProtKB/TrEMBL
      A0A0G2K8M7, Q499Q2
      Conserved Domains (1) summary
      pfam04201
      Location:12156
      TPD52; Tumour protein D52 family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      27991114..28109767
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006227737.5XP_006227799.1  tumor protein D53 isoform X2

      Related
      ENSRNOP00000035722.5, ENSRNOT00000030327.5
      Conserved Domains (1) summary
      pfam04201
      Location:12187
      TPD52; Tumour protein D52 family
    2. XM_008758674.4XP_008756896.1  tumor protein D53 isoform X3

      See identical proteins and their annotated locations for XP_008756896.1

      UniProtKB/TrEMBL
      A0A8I6AAC3, A6JUR6
      Related
      ENSRNOP00000090569.1, ENSRNOT00000116457.2
      Conserved Domains (1) summary
      pfam04201
      Location:12174
      TPD52; Tumour protein D52 family
    3. XM_039091345.2XP_038947273.1  tumor protein D53 isoform X4

      UniProtKB/TrEMBL
      A0A0G2K8M7
      Related
      ENSRNOP00000087430.2, ENSRNOT00000094990.2
      Conserved Domains (1) summary
      pfam04201
      Location:12161
      TPD52; tumor protein D52 family
    4. XM_006227739.5XP_006227801.1  tumor protein D53 isoform X1

      UniProtKB/TrEMBL
      F7FE56
      Related
      ENSRNOP00000082009.2, ENSRNOT00000107523.2
      Conserved Domains (1) summary
      pfam04201
      Location:12192
      TPD52; Tumour protein D52 family
    5. XM_063274594.1XP_063130664.1  tumor protein D53 isoform X5

      UniProtKB/TrEMBL
      A0A8I6AJ07
    6. XM_063274598.1XP_063130668.1  tumor protein D53 isoform X6

      UniProtKB/TrEMBL
      A0A0G2K8M7, A0A8I5XV74, A6JUR7
      Related
      ENSRNOP00000074667.3, ENSRNOT00000078841.3
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