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    Arl14ep ARF like GTPase 14 effector protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 311279, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Arl14epprovided by RGD
    Official Full Name
    ARF like GTPase 14 effector proteinprovided by RGD
    Primary source
    RGD:1311463
    See related
    EnsemblRapid:ENSRNOG00000004891 AllianceGenome:RGD:1311463
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    ARF7EP; RGD1311463
    Summary
    Predicted to be located in several cellular components, including cytosol; focal adhesion; and nuclear lumen. Predicted to be active in intracellular membrane-bounded organelle. Orthologous to human ARL14EP (ADP ribosylation factor like GTPase 14 effector protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 108.1), Heart (RPKM 95.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Arl14ep in Genome Data Viewer
    Location:
    3q33
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (113896731..113908994, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (93441952..93454282, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (97981506..97993684, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene doublecortin domain containing 1, pseudogene 1 Neighboring gene doublecortin domain containing 1 Neighboring gene metallophosphoesterase domain containing 2 Neighboring gene histidine triad nucleotide binding protein 1, pseudogene 4 Neighboring gene uncharacterized LOC134486417 Neighboring gene follicle stimulating hormone subunit beta

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC109199

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in focal adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in focal adhesion ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    ARL14 effector protein
    Names
    ADP-ribosylation factor like GTPase 14 effector protein
    ADP-ribosylation factor-like 14 effector protein
    ARF7 effector protein
    uncharacterized protein C11orf46 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014045.1 → NP_001014067.1  ARL14 effector protein

      See identical proteins and their annotated locations for NP_001014067.1

      Status: PROVISIONAL

      Source sequence(s)
      BC089920
      UniProtKB/Swiss-Prot
      Q5FVK8
      UniProtKB/TrEMBL
      A6HNZ2
      Conserved Domains (1) summary
      pfam14949
      Location:145 → 248
      ARF7EP_C; ARF7 effector protein C-terminus

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      113896731..113908994 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039104930.2 → XP_038960858.1  ARL14 effector protein isoform X1

      Related
      ENSRNOP00000006481.5, ENSRNOT00000006481.6
      Conserved Domains (1) summary
      pfam14949
      Location:145 → 248
      ARF7EP_C; ARF7 effector protein C-terminus

    2. XM_039104931.2 → XP_038960859.1  ARL14 effector protein isoform X1

      Conserved Domains (1) summary
      pfam14949
      Location:145 → 248
      ARF7EP_C; ARF7 effector protein C-terminus

    3. XM_063283707.1 → XP_063139777.1  ARL14 effector protein isoform X2

      UniProtKB/Swiss-Prot
      Q5FVK8
      UniProtKB/TrEMBL
      A6HNZ2

    RNA

    1. XR_005501868.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5FVK8.1 GenPept UniProtKB/Swiss-Prot:Q5FVK8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
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