Pim2 Pim-2 proto-oncogene, serine/threonine kinase [Rattus norvegicus (Norway rat)] - Gene

Summary

Gene symbol: Pim2
Gene description: Pim-2 proto-oncogene, serine/threonine kinase
See related: EnsemblRapid:ENSRNOG00000008177
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression: Biased expression in Brain (RPKM 55.6), Spleen (RPKM 35.3) and 8 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: Xq12

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	X	NC_086039.1 (17289509..17294778, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	X	NC_051356.1 (14617582..14622851, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	X	NC_005120.4 (15462621..15467890, complement)

Chromosome X - NC_086039.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

Pim2 (e-PCR), detects polymorphism
- UniSTS:463219

General protein information

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Preferred Names: serine/threonine-protein kinase pim-2

Names: pim-2 oncogene

NP_001165574.1

EC 2.7.11.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001172103.1 → NP_001165574.1 serine/threonine-protein kinase pim-2

Status: VALIDATED

Source sequence(s)

JAXUCZ010000021

UniProtKB/TrEMBL

A6KP72, F1M419

Related

ENSRNOP00000011207.6, ENSRNOT00000011207.9

Conserved Domains (2) summary

smart00220
Location:32 → 286

S_TKc; Serine/Threonine protein kinases, catalytic domain

cl21453
Location:31 → 287

PKc_like; Protein Kinases, catalytic domain