Gstt3 glutathione S-transferase, theta 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Gstt3provided by RGD
Official Full Name: glutathione S-transferase, theta 3provided by RGD
Primary source: RGD:1562732
See related: EnsemblRapid:ENSRNOG00000001242 AllianceGenome:RGD:1562732
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1562732
Expression: Biased expression in Kidney (RPKM 991.7), Adrenal (RPKM 614.9) and 5 other tissues See more
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Genomic context

Location:: 20p12

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	20	NC_086038.1 (12873618..12881974)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	20	NC_051355.1 (12875184..12882540)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	20	NC_005119.4 (13817795..13825475)

Chromosome 20 - NC_086038.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Gstt3 could predict inter-individual susceptibility to D-galactosamine induced hepatotoxicity
Title: Expression levels of pituitary tumor transforming 1 and glutathione-S-transferase theta 3 are associated with the individual susceptibility to D-galactosamine-induced hepatotoxicity.

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General gene information

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Markers

RH128155 (e-PCR)
- UniSTS:211463

RH130749 (e-PCR)
- UniSTS:214033

RH133843 (e-PCR)
- UniSTS:217126

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables glutathione transferase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in glutathione metabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: glutathione S-transferase, theta 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001399042.1 → NP_001385971.1 glutathione S-transferase, theta 3

Status: VALIDATED

Source sequence(s)

JAXUCZ010000020

UniProtKB/TrEMBL

A0A8I5ZLR0

Related

ENSRNOP00000094988.2, ENSRNOT00000114782.2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086038.1 Reference GRCr8

Range

12873618..12881974

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063279467.1 → XP_063135537.1 glutathione S-transferase, theta 3 isoform X2
XM_063279466.1 → XP_063135536.1 glutathione S-transferase, theta 3 isoform X1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001137643.1: Suppressed sequence

Description

NM_001137643.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.