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    Zrsr2-ps1 zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2, pseudogene 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498425, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zrsr2-ps1provided by RGD
    Official Full Name
    zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2, pseudogene 1provided by RGD
    Primary source
    RGD:1561824
    See related
    AllianceGenome:RGD:1561824
    Gene type
    pseudo
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Zrsr1
    Summary
    Predicted to enable pre-mRNA 3'-splice site binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of U12-type spliceosomal complex and U2AF complex. Human ortholog(s) of this gene implicated in acute myeloid leukemia and myelodysplastic syndrome. Orthologous to human ZRSR2P1 (ZRSR2 pseudogene 1) and ZRSR2 (zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 131.4), Heart (RPKM 111.8) and 9 other tissues See more
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    Genomic context

    See Zrsr2-ps1 in Genome Data Viewer
    Location:
    14q22
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (101173861..101179999)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (96972651..96978364)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (107750162..107751895)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102552414 Neighboring gene copper metabolism domain containing 1 Neighboring gene uncharacterized LOC134481876 Neighboring gene uncharacterized LOC134481877 Neighboring gene uncharacterized LOC120096694 Neighboring gene chaperonin containing TCP1 subunit 4 Neighboring gene FAM161 centrosomal protein A

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Other Names

    • U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1
    • zinc finger (CCCH type), RNA binding motif and serine/arginine rich 1

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables pre-mRNA 3'-splice site binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of U12-type spliceosomal complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U2AF complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of spliceosomal complex ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      101173861..101179999
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_010057752.1 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001017504.1: Suppressed sequence

      Description
      NM_001017504.1: This RefSeq was removed because it is now thought that this gene is a pseudogene.