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    Sult2a2 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361510, updated on 9-Dec-2024

    Summary

    Official Symbol
    Sult2a2provided by RGD
    Official Full Name
    sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2provided by RGD
    Primary source
    RGD:1306542
    See related
    EnsemblRapid:ENSRNOG00000062869 AllianceGenome:RGD:1306542
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    DST; SMP-2; ST2A2
    Summary
    Predicted to enable alcohol sulfotransferase activity. Predicted to be involved in steroid metabolic process. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human SULT2A1 (sulfotransferase family 2A member 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 3412.4) See more
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    Genomic context

    See Sult2a2 in Genome Data Viewer
    Location:
    1q21
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (85037518..85104532, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (75909585..75976600, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (76252329..76517193, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene nucleolin, pseudogene 3 Neighboring gene signal recognition particle 72, pseudogene 1 Neighboring gene sulfotransferase family 2A member 1 Neighboring gene nucleolin, pseudogene 2 Neighboring gene U6 spliceosomal RNA Neighboring gene transfer RNA glycine (anticodon ACC) 2 Neighboring gene signal recognition particle subunit SRP72-like Neighboring gene nucleolin-like

    Genomic regions, transcripts, and products

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables alcohol sulfotransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables sulfotransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in steroid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    sulfotransferase 2A2
    Names
    Androgen-repressible liver protein
    Dehydroepiandrosterone sulfotransferase
    Probable alcohol sulfotransferase
    ST
    ST-60
    Senescence marker protein 2
    alcohol sulfotransferase
    alcohol sulfotransferase-like
    hydroxysteroid sulfotransferase
    NP_001020302.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025131.2NP_001020302.1  sulfotransferase 2A2

      See identical proteins and their annotated locations for NP_001020302.1

      Status: PROVISIONAL

      Source sequence(s)
      D14989
      UniProtKB/Swiss-Prot
      O09038, P07631, P50235, Q04169
      UniProtKB/TrEMBL
      D3ZR55
      Related
      ENSRNOP00000082415.1, ENSRNOT00000110958.2
      Conserved Domains (1) summary
      pfam00685
      Location:34278
      Sulfotransfer_1; Sulfotransferase domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      85037518..85104532 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)