Frem3 FRAS1 related extracellular matrix 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Frem3provided by RGD
Official Full Name: FRAS1 related extracellular matrix 3provided by RGD
Primary source: RGD:1562701
See related: EnsemblRapid:ENSRNOG00000039152 AllianceGenome:RGD:1562701
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1562701
Summary: Predicted to be involved in anatomical structure morphogenesis. Predicted to be located in basement membrane. Predicted to be active in collagen-containing extracellular matrix. Orthologous to human FREM3 (FRAS1 related extracellular matrix 3). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Brain (RPKM 1.1), Testes (RPKM 0.9) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 19q11

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	19	NC_086037.1 (44212842..44271137, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	19	NC_051354.1 (27308469..27366771, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	19	NC_005118.4 (30973329..31032331, complement)

Chromosome 19 - NC_086037.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

D19Rat110 (e-PCR), detects polymorphism
- UniSTS:226972

RH142598 (e-PCR)
- UniSTS:231845

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in anatomical structure morphogenesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in cell adhesion	IEA Inferred from Electronic Annotation more info
involved_in cell communication	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in basement membrane	ISO Inferred from Sequence Orthology more info
is_active_in collagen-containing extracellular matrix	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: FRAS1-related extracellular matrix protein 3

Names: Fras1 related extracellular matrix protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001191699.1 → NP_001178628.1 FRAS1-related extracellular matrix protein 3 precursor

Status: PROVISIONAL

Source sequence(s)

JAXUCZ010000019

UniProtKB/TrEMBL

D3ZYN7

Related

ENSRNOP00000056641.3, ENSRNOT00000059896.5

Conserved Domains (2) summary

pfam16184
Location:1473 → 1614

Cadherin_3; Cadherin-like

cl02522
Location:2004 → 2094

Calx-beta; Calx-beta domain