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    Tmem131 transmembrane protein 131 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 316335, updated on 9-Dec-2024

    Summary

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    Symbol
    Tmem131provided by RGD
    Full Name
    transmembrane protein 131provided by RGD
    Primary source
    RGD:1309266
    See related
    EnsemblRapid:ENSRNOG00000017265 AllianceGenome:RGD:1309266
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309266
    Summary
    Predicted to enable collagen binding activity. Predicted to be involved in collagen biosynthetic process. Predicted to be active in membrane. Orthologous to human TMEM131 (transmembrane protein 131). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 141.2), Spleen (RPKM 131.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tmem131 in Genome Data Viewer
    Location:
    9q21
    Exon count:
    43
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (46512328..46658624, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (39016470..39162841, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (43357866..43515317, complement)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene similar to human chromosome 2 open reading frame 92 Neighboring gene U4 spliceosomal RNA Neighboring gene zeta chain of T cell receptor associated protein kinase 70 Neighboring gene uncharacterized LOC134480356 Neighboring gene von Willebrand factor A domain containing 3B Neighboring gene transfer RNA alanine (anticodon AGC) 41

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables collagen binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in collagen biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 131

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427652.1 → NP_001414581.1  transmembrane protein 131

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A0A8I5ZM29, A6INF6
      Related
      ENSRNOP00000079056.1, ENSRNOT00000112888.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      46512328..46658624 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006244855.5 → XP_006244917.1  transmembrane protein 131 isoform X1

      See identical proteins and their annotated locations for XP_006244917.1

      UniProtKB/TrEMBL
      A6INF6
      Conserved Domains (2) summary
      pfam10500
      Location:1272 → 1470
      SR-25; Nuclear RNA-splicing-associated protein
      pfam12371
      Location:106 → 188
      TMEM131_like; Transmembrane protein 131-like

    2. XM_006244858.5 → XP_006244920.1  transmembrane protein 131 isoform X2

      See identical proteins and their annotated locations for XP_006244920.1

      UniProtKB/TrEMBL
      A0A8I6ACW0, A6INF6
      Related
      ENSRNOP00000090966.1, ENSRNOT00000093761.2
      Conserved Domains (2) summary
      pfam10500
      Location:1206 → 1404
      SR-25; Nuclear RNA-splicing-associated protein
      pfam12371
      Location:40 → 122
      TMEM131_like; Transmembrane protein 131-like

    3. XM_039084533.2 → XP_038940461.1  transmembrane protein 131 isoform X3

      UniProtKB/TrEMBL
      A6INF6
      Conserved Domains (1) summary
      cl13764
      Location:106 → 188
      ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
    Nucleotide Protein Strain
    Heading Accession and Version

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