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    Praf2 PRA1 domain family, member 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 367743, updated on 9-Dec-2024

    Summary

    Official Symbol
    Praf2provided by RGD
    Official Full Name
    PRA1 domain family, member 2provided by RGD
    Primary source
    RGD:1566287
    See related
    EnsemblRapid:ENSRNOG00000057147 AllianceGenome:RGD:1566287
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1566287
    Summary
    Predicted to be active in several cellular components, including GABA-ergic synapse; glutamatergic synapse; and postsynapse. Orthologous to human PRAF2 (PRA1 domain family member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 92.8), Lung (RPKM 34.6) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Praf2 in Genome Data Viewer
    Location:
    Xq12
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (17445313..17447950, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (14773398..14776035, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (15618324..15620992, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134484176 Neighboring gene coiled-coil domain containing 120 Neighboring gene WD repeat domain 45 Neighboring gene G patch domain and KOW motifs

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in GABA-ergic synapse ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in postsynapse ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in presynapse ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    PRA1 family protein 2
    Names
    PRA1 domain family 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109013.1NP_001102483.1  PRA1 family protein 2

      See identical proteins and their annotated locations for NP_001102483.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474078
      UniProtKB/TrEMBL
      A0A0G2JTX2, A6KP85
      Related
      ENSRNOP00000068878.2, ENSRNOT00000085397.3
      Conserved Domains (1) summary
      pfam03208
      Location:4148
      PRA1; PRA1 family protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      17445313..17447950 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)