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    Bclaf3 BCLAF1 and THRAP3 family member 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 501559, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Bclaf3provided by RGD
    Official Full Name
    BCLAF1 and THRAP3 family member 3provided by RGD
    Primary source
    RGD:1562161
    See related
    EnsemblRapid:ENSRNOG00000005135 AllianceGenome:RGD:1562161
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1562161
    Summary
    Predicted to enable DNA binding activity and transcription coregulator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be part of mediator complex. Orthologous to human BCLAF3 (BCLAF1 and THRAP3 family member 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 43.3), Spleen (RPKM 40.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Bclaf3 in Genome Data Viewer
    Location:
    Xq14
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (39065842..39137521, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (35257228..35328883, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (38294009..38353525, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase kinase kinase 15 Neighboring gene ubiquitin-like 4A, pseudogene Neighboring gene SH3 domain-containing kinase-binding protein 1 Neighboring gene ribosomal protein S9, pseudogene 13 Neighboring gene MAP7 domain containing 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    BCLAF1 and THRAP3 family member 3
    Names
    uncharacterized protein CXorf23 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001127568.1 → NP_001121040.1  BCLAF1 and THRAP3 family member 3

      See identical proteins and their annotated locations for NP_001121040.1

      Status: PROVISIONAL

      Source sequence(s)
      BC166438
      UniProtKB/TrEMBL
      A6IPM9, B2GUW9, E9PSU1
      Related
      ENSRNOP00000006867.6, ENSRNOT00000006867.8
      Conserved Domains (1) summary
      pfam15440
      Location:3 → 654
      THRAP3_BCLAF1; THRAP3/BCLAF1 family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      39065842..39137521 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039099968.2 → XP_038955896.1  BCLAF1 and THRAP3 family member 3 isoform X1

      UniProtKB/TrEMBL
      A6IPM9, B2GUW9, E9PSU1
      Conserved Domains (1) summary
      pfam15440
      Location:3 → 654
      THRAP3_BCLAF1; THRAP3/BCLAF1 family

    2. XM_039099970.2 → XP_038955898.1  BCLAF1 and THRAP3 family member 3 isoform X2

      UniProtKB/TrEMBL
      A6IPM9
      Conserved Domains (1) summary
      pfam15440
      Location:3 → 653
      THRAP3_BCLAF1; THRAP3/BCLAF1 family

    3. XM_039099972.2 → XP_038955900.1  BCLAF1 and THRAP3 family member 3 isoform X3

      UniProtKB/TrEMBL
      A6IPM9
      Conserved Domains (1) summary
      pfam15440
      Location:3 → 625
      THRAP3_BCLAF1; THRAP3/BCLAF1 family

    4. XM_039099973.2 → XP_038955901.1  BCLAF1 and THRAP3 family member 3 isoform X4

      UniProtKB/TrEMBL
      A0A8I6ASV7, A6IPM9
      Related
      ENSRNOP00000097547.1, ENSRNOT00000114369.2
      Conserved Domains (1) summary
      pfam15440
      Location:3 → 654
      THRAP3_BCLAF1; THRAP3/BCLAF1 family
    Nucleotide Protein Strain
    Heading Accession and Version

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