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    Gpatch4 G patch domain containing 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 295228, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Gpatch4provided by RGD
    Official Full Name
    G patch domain containing 4provided by RGD
    Primary source
    RGD:1311086
    See related
    EnsemblRapid:ENSRNOG00000018969 AllianceGenome:RGD:1311086
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1311086
    Summary
    Predicted to enable nucleic acid binding activity. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Predicted to be located in nucleoplasm. Predicted to be active in nucleolus. Orthologous to human GPATCH4 (G-patch domain containing 4 (gene/pseudogene)). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 40.4), Brain (RPKM 35.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Gpatch4 in Genome Data Viewer
    Location:
    2q34
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (175797503..175816547)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (173499700..173520346)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (187404731..187424047)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene brevican Neighboring gene hyaluronan and proteoglycan link protein 2 Neighboring gene NAD(P)HX epimerase Neighboring gene tetratricopeptide repeat domain 24

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Nagamachi A, et al. Cancer Cell, 2013 Sep 9. PMID 24029230
    2. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, et al. Cell, 2012 Jun 8. PMID 22658674
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within hematopoietic progenitor cell differentiation ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    G patch domain-containing protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024979.1 → NP_001020150.1  G patch domain-containing protein 4

      See identical proteins and their annotated locations for NP_001020150.1

      Status: PROVISIONAL

      Source sequence(s)
      BC093381
      UniProtKB/Swiss-Prot
      Q566R3
      UniProtKB/TrEMBL
      A6J647
      Related
      ENSRNOP00000053762.3, ENSRNOT00000056923.4
      Conserved Domains (1) summary
      pfam01585
      Location:8 → 55
      G-patch; G-patch domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      175797503..175816547
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063281605.1 → XP_063137675.1  G patch domain-containing protein 4 isoform X1

      UniProtKB/Swiss-Prot
      Q566R3
      UniProtKB/TrEMBL
      A6J647

    2. XM_063281602.1 → XP_063137672.1  G patch domain-containing protein 4 isoform X1

      UniProtKB/Swiss-Prot
      Q566R3
      UniProtKB/TrEMBL
      A6J647

    3. XM_063281601.1 → XP_063137671.1  G patch domain-containing protein 4 isoform X1

      UniProtKB/Swiss-Prot
      Q566R3
      UniProtKB/TrEMBL
      A6J647

    4. XM_063281600.1 → XP_063137670.1  G patch domain-containing protein 4 isoform X1

      UniProtKB/Swiss-Prot
      Q566R3
      UniProtKB/TrEMBL
      A6J647

    5. XM_063281603.1 → XP_063137673.1  G patch domain-containing protein 4 isoform X1

      UniProtKB/Swiss-Prot
      Q566R3
      UniProtKB/TrEMBL
      A6J647

    6. XM_063281604.1 → XP_063137674.1  G patch domain-containing protein 4 isoform X1

      UniProtKB/Swiss-Prot
      Q566R3
      UniProtKB/TrEMBL
      A6J647

    7. XM_008761132.4 → XP_008759354.1  G patch domain-containing protein 4 isoform X1

      See identical proteins and their annotated locations for XP_008759354.1

      UniProtKB/Swiss-Prot
      Q566R3
      UniProtKB/TrEMBL
      A6J647
      Conserved Domains (1) summary
      pfam01585
      Location:8 → 55
      G-patch; G-patch domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q566R3.1 GenPept UniProtKB/Swiss-Prot:Q566R3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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