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    Tmem214 transmembrane protein 214 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362711, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tmem214provided by RGD
    Official Full Name
    transmembrane protein 214provided by RGD
    Primary source
    RGD:1311324
    See related
    EnsemblRapid:ENSRNOG00000008812 AllianceGenome:RGD:1311324
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1311324
    Summary
    Predicted to be involved in apoptotic process. Predicted to be located in cytoplasmic microtubule and cytosol. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Orthologous to human TMEM214 (transmembrane protein 214). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 148.9), Lung (RPKM 107.0) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tmem214 in Genome Data Viewer
    Location:
    6q14
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (31222635..31231659, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (25501575..25510444, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (26867638..26875384, complement)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene AGBL carboxypeptidase 5 Neighboring gene transfer RNA tyrosine (anticodon GUA) 3 Neighboring gene uncharacterized LOC134479111 Neighboring gene microtubule-associated protein, RP/EB family, member 3 Neighboring gene uncharacterized LOC108351190 Neighboring gene uncharacterized LOC108351187 Neighboring gene 60S ribosomal protein L37 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. MTR120/KIAA1383, a novel microtubule-associated protein, promotes microtubule stability and ensures cytokinesis. Fong KW, et al. J Cell Sci, 2013 Feb 1. PMID 23264731, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasmic microtubule ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasmic microtubule ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 214

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014195.2 → NP_001014217.2  transmembrane protein 214

      See identical proteins and their annotated locations for NP_001014217.2

      Status: PROVISIONAL

      Source sequence(s)
      BC129115
      UniProtKB/Swiss-Prot
      A1L1L2, Q5U4F5
      UniProtKB/TrEMBL
      A0A8I5ZZM7, A6HAC0
      Related
      ENSRNOP00000011838.5, ENSRNOT00000011838.8
      Conserved Domains (1) summary
      pfam10151
      Location:215 → 681
      DUF2359; uncharacterized conserved protein (DUF2359)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      31222635..31231659 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063262060.1 → XP_063118130.1  transmembrane protein 214 isoform X1

      UniProtKB/Swiss-Prot
      A1L1L2, Q5U4F5
      UniProtKB/TrEMBL
      A0A8I5ZZM7, A6HAC0

    2. XM_063262061.1 → XP_063118131.1  transmembrane protein 214 isoform X2

    RNA

    1. XR_010052105.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1L1L2.1 GenPept UniProtKB/Swiss-Prot:A1L1L2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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