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    Xlr4a X-linked lymphocyte-regulated 4A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 293841, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Xlr4aprovided by RGD
    Official Full Name
    X-linked lymphocyte-regulated 4Aprovided by RGD
    Primary source
    RGD:1565442
    See related
    EnsemblRapid:ENSRNOG00000055822 AllianceGenome:RGD:1565442
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1565442
    Summary
    Predicted to be involved in meiotic cell cycle and spermatid development. Predicted to be active in synaptonemal complex. Orthologous to human FAM9A (family with sequence similarity 9 member A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 13.2), Thymus (RPKM 1.1) and 3 other tissues See more
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    Genomic context

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    See Xlr4a in Genome Data Viewer
    Location:
    Xq37
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (155958900..155967302, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (150916647..150925201, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (153072965..153081324, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene PNMA family member 5 Neighboring gene PNMA family member 3 Neighboring gene coagulation factor VIII-associated 1 Neighboring gene X-linked lymphocyte-regulated protein 3A-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in meiotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in spermatid development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in synaptonemal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    X-linked lymphocyte-regulated 4A; X-linked lymphocyte-regulated protein 3A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001432858.1 → NP_001419787.1  X-linked lymphocyte-regulated 4A

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/TrEMBL
      A6KSZ1, D4A7L7

    2. NM_001432859.1 → NP_001419788.1  X-linked lymphocyte-regulated 4A

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/TrEMBL
      A6KSZ1, D4A7L7

    3. NM_001432861.1 → NP_001419790.1  X-linked lymphocyte-regulated 4A

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/TrEMBL
      A6KSZ1, D4A7L7

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      155958900..155967302 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006229528.5 → XP_006229590.1  X-linked lymphocyte-regulated protein 3A isoform X1

      See identical proteins and their annotated locations for XP_006229590.1

      UniProtKB/TrEMBL
      A6KSZ1, D4A7L7
      Conserved Domains (1) summary
      pfam04803
      Location:63 → 177
      Cor1; Cor1/Xlr/Xmr conserved region

    2. XM_219738.10 → XP_219738.6  X-linked lymphocyte-regulated protein 3A isoform X2

      UniProtKB/TrEMBL
      D4A7L7
      Conserved Domains (1) summary
      pfam04803
      Location:76 → 190
      Cor1; Cor1/Xlr/Xmr conserved region

    3. XM_006229524.5 → XP_006229586.1  X-linked lymphocyte-regulated protein 3A isoform X1

      Related
      ENSRNOP00000069444.3, ENSRNOT00000091365.3
      Conserved Domains (1) summary
      pfam04803
      Location:63 → 177
      Cor1; Cor1/Xlr/Xmr conserved region

    4. XM_006229523.5 → XP_006229585.1  X-linked lymphocyte-regulated protein 3A isoform X1

      Conserved Domains (1) summary
      pfam04803
      Location:63 → 177
      Cor1; Cor1/Xlr/Xmr conserved region
    Nucleotide Protein Strain
    Heading Accession and Version

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