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    Ccdc57 coiled-coil domain containing 57 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 688324, updated on 9-Dec-2024

    Summary

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    Symbol
    Ccdc57provided by RGD
    Full Name
    coiled-coil domain containing 57provided by RGD
    Primary source
    RGD:1590047
    See related
    EnsemblRapid:ENSRNOG00000047531 AllianceGenome:RGD:1590047
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in several processes, including G2/M transition of mitotic cell cycle; cilium assembly; and microtubule cytoskeleton organization. Predicted to be located in centriolar satellite; centriole; and spindle microtubule. Orthologous to human CCDC57 (coiled-coil domain containing 57). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 47.6), Kidney (RPKM 30.7) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ccdc57 in Genome Data Viewer
    Location:
    10q32.3
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (106591106..106694740, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (106092784..106196405, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (110046012..110110775, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120095225 Neighboring gene fatty acid synthase Neighboring gene dolichyl-phosphate mannosyltransferase subunit 3, regulatory, pseudogene 2 Neighboring gene solute carrier family 16 member 3 Neighboring gene casein kinase 1, delta

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in G2/M transition of mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in centriole replication IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in centriole replication ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cilium assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in microtubule nucleation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in microtubule nucleation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in centriolar satellite IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in centriole IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in centriole ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in spindle microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in spindle microtubule ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil domain containing 57; coiled-coil domain-containing protein 57

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      106591106..106694740 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063270205.1 → XP_063126275.1  coiled-coil domain-containing protein 57 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZSM9

    2. XM_063270202.1 → XP_063126272.1  coiled-coil domain-containing protein 57 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZSM9

    3. XM_063270204.1 → XP_063126274.1  coiled-coil domain-containing protein 57 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZSM9

    4. XM_039087556.2 → XP_038943484.1  coiled-coil domain-containing protein 57 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZSM9
      Conserved Domains (3) summary
      PHA03307
      Location:911 → 1135
      PHA03307; transcriptional regulator ICP4; Provisional
      COG1196
      Location:28 → 718
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:53 → 394
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    5. XM_039087567.2 → XP_038943495.1  coiled-coil domain-containing protein 57 isoform X9

      UniProtKB/TrEMBL
      A0A8I5ZSM9
      Conserved Domains (3) summary
      PHA03307
      Location:778 → 1002
      PHA03307; transcriptional regulator ICP4; Provisional
      COG1196
      Location:126 → 409
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:195 → 584
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    6. XM_039087568.2 → XP_038943496.1  coiled-coil domain-containing protein 57 isoform X9

      UniProtKB/TrEMBL
      A0A8I5ZSM9
      Conserved Domains (3) summary
      PHA03307
      Location:778 → 1002
      PHA03307; transcriptional regulator ICP4; Provisional
      COG1196
      Location:126 → 409
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:195 → 584
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    7. XM_039087565.2 → XP_038943493.1  coiled-coil domain-containing protein 57 isoform X7

      UniProtKB/TrEMBL
      A0A8I5ZSM9
      Conserved Domains (2) summary
      PHA03307
      Location:816 → 1040
      PHA03307; transcriptional regulator ICP4; Provisional
      COG1196
      Location:28 → 623
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    8. XM_039087563.2 → XP_038943491.1  coiled-coil domain-containing protein 57 isoform X6

      UniProtKB/TrEMBL
      M0R9E4
      Conserved Domains (2) summary
      PHA03307
      Location:841 → 1065
      PHA03307; transcriptional regulator ICP4; Provisional
      TIGR02168
      Location:36 → 744
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    9. XM_039087559.2 → XP_038943487.1  coiled-coil domain-containing protein 57 isoform X3

      UniProtKB/TrEMBL
      A0A8I5ZSM9
      Conserved Domains (3) summary
      PHA03307
      Location:883 → 1107
      PHA03307; transcriptional regulator ICP4; Provisional
      COG1196
      Location:321 → 690
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:53 → 394
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    10. XM_063270211.1 → XP_063126281.1  coiled-coil domain-containing protein 57 isoform X10

      UniProtKB/TrEMBL
      M0R9E4

    11. XM_063270209.1 → XP_063126279.1  coiled-coil domain-containing protein 57 isoform X10

      UniProtKB/TrEMBL
      M0R9E4

    12. XM_063270210.1 → XP_063126280.1  coiled-coil domain-containing protein 57 isoform X10

      UniProtKB/TrEMBL
      M0R9E4

    13. XM_063270208.1 → XP_063126278.1  coiled-coil domain-containing protein 57 isoform X10

      UniProtKB/TrEMBL
      M0R9E4

    14. XM_063270206.1 → XP_063126276.1  coiled-coil domain-containing protein 57 isoform X10

      UniProtKB/TrEMBL
      M0R9E4

    15. XM_063270207.1 → XP_063126277.1  coiled-coil domain-containing protein 57 isoform X10

      UniProtKB/TrEMBL
      M0R9E4

    16. XM_039087569.2 → XP_038943497.1  coiled-coil domain-containing protein 57 isoform X11

      UniProtKB/TrEMBL
      M0R9E4
      Conserved Domains (3) summary
      PHA03307
      Location:649 → 873
      PHA03307; transcriptional regulator ICP4; Provisional
      COG1196
      Location:1 → 280
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:66 → 455
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    17. XM_039087566.2 → XP_038943494.1  coiled-coil domain-containing protein 57 isoform X8

      UniProtKB/TrEMBL
      M0R9E4
      Related
      ENSRNOP00000066112.4, ENSRNOT00000071893.4
      Conserved Domains (2) summary
      PHA03307
      Location:813 → 1037
      PHA03307; transcriptional regulator ICP4; Provisional
      COG1196
      Location:28 → 620
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    18. XM_039087571.2 → XP_038943499.1  coiled-coil domain-containing protein 57 isoform X12

      Conserved Domains (2) summary
      PHA03307
      Location:566 → 790
      PHA03307; transcriptional regulator ICP4; Provisional
      COG1196
      Location:3 → 373
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    19. XM_063270203.1 → XP_063126273.1  coiled-coil domain-containing protein 57 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZSM9
      Related
      ENSRNOP00000091858.2, ENSRNOT00000098223.2

    20. XM_039087570.1 → XP_038943498.1  coiled-coil domain-containing protein 57 isoform X11

      UniProtKB/TrEMBL
      M0R9E4
      Conserved Domains (3) summary
      PHA03307
      Location:649 → 873
      PHA03307; transcriptional regulator ICP4; Provisional
      COG1196
      Location:1 → 280
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:66 → 455
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    21. XM_039087561.2 → XP_038943489.1  coiled-coil domain-containing protein 57 isoform X4

      UniProtKB/TrEMBL
      A0A8I5ZSM9
      Conserved Domains (2) summary
      COG1196
      Location:28 → 718
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:53 → 394
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    22. XM_039087562.2 → XP_038943490.1  coiled-coil domain-containing protein 57 isoform X5

      UniProtKB/TrEMBL
      A0A8I5Y209
      Conserved Domains (2) summary
      COG1196
      Location:28 → 718
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:53 → 394
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    23. XM_039087572.2 → XP_038943500.1  coiled-coil domain-containing protein 57 isoform X13

      Conserved Domains (1) summary
      TIGR02168
      Location:53 → 394
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    RNA

    1. XR_010055923.1 RNA Sequence

    2. XR_005490602.2 RNA Sequence

    3. XR_005490603.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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