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    Armt1 acidic residue methyltransferase 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 292267, updated on 9-Dec-2024

    Summary

    Official Symbol
    Armt1provided by RGD
    Official Full Name
    acidic residue methyltransferase 1provided by RGD
    Primary source
    RGD:1305235
    See related
    EnsemblRapid:ENSRNOG00000019489 AllianceGenome:RGD:1305235
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305235
    Summary
    Predicted to enable enzyme binding activity; methyltransferase activity; and phosphatase activity. Predicted to be involved in DNA damage response. Orthologous to human ARMT1 (acidic residue methyltransferase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 129.7), Testes (RPKM 100.0) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Armt1 in Genome Data Viewer
    Location:
    1q11
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (43299916..43323675)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (40894558..40918302)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (40982761..41006371)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene zinc finger and BTB domain containing 2 Neighboring gene zinc finger and BTB domain containing 2 like Neighboring gene required for meiotic nuclear division 1 homolog Neighboring gene uncharacterized LOC134482620 Neighboring gene coiled-coil domain containing 170 Neighboring gene estrogen receptor 1 Neighboring gene uncharacterized LOC134482628

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables S-adenosylmethionine-dependent methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables S-adenosylmethionine-dependent methyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables S-adenosylmethionine-dependent methyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables enzyme binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables fructose 6-phosphate aldolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables fructose-1-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein carboxyl O-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein carboxyl O-methyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein carboxyl O-methyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables protein-glutamate O-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in DNA damage response IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in DNA damage response IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in DNA damage response ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in DNA damage response ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    damage-control phosphatase ARMT1
    Names
    UPF0364 protein C6orf211 homolog
    protein-glutamate O-methyltransferase
    sugar phosphate phosphatase ARMT1
    NP_001017447.1
    XP_006227895.1
    XP_017444359.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017447.1NP_001017447.1  damage-control phosphatase ARMT1

      See identical proteins and their annotated locations for NP_001017447.1

      Status: PROVISIONAL

      Source sequence(s)
      BC078920
      UniProtKB/Swiss-Prot
      Q6AYT5
      UniProtKB/TrEMBL
      A0A8I6A1F9, A6KIL4
      Related
      ENSRNOP00000026367.4, ENSRNOT00000026367.8
      Conserved Domains (1) summary
      pfam01937
      Location:20417
      DUF89; Protein of unknown function DUF89

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      43299916..43323675
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017588870.2XP_017444359.1  damage-control phosphatase ARMT1 isoform X2

      UniProtKB/TrEMBL
      A6KIL7
    2. XM_006227833.5XP_006227895.1  damage-control phosphatase ARMT1 isoform X1

      UniProtKB/TrEMBL
      A6KIL7
      Conserved Domains (1) summary
      pfam01937
      Location:78359
      DUF89; Protein of unknown function DUF89

    RNA

    1. XR_010064171.1 RNA Sequence