Mpp1 MAGUK p55 scaffold protein 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Mpp1provided by RGD
Official Full Name: MAGUK p55 scaffold protein 1provided by RGD
Primary source: RGD:1594331
See related: AllianceGenome:RGD:1594331
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: p55
Summary: Predicted to be involved in regulation of neutrophil chemotaxis. Predicted to be located in centriolar satellite; cortical cytoskeleton; and plasma membrane. Orthologous to human MPP1 (MAGUK p55 scaffold protein 1). [provided by Alliance of Genome Resources, Dec 2024]
Annotation information: not in current annotation release
Expression: Biased expression in Kidney (RPKM 241.8), Spleen (RPKM 231.3) and 9 other tissues See more
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Genomic context

Location:: 1q31

Annotation release	Status	Assembly	Chr	Location
106	latest, but not current	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (148450213..148458945)
106	latest, but not current	Rn_Celera (GCF_000002265.2)	1	AC_000069.1 (137539255..137547772)

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Intragastric denatonium benzoate increases neuronal c-Fos expression in the nucleus tractus solitarius 1 h after gavage and this effect is mediated by vagal afferent fibers.
Title: Intragastric gavage with denatonium benzoate acutely induces neuronal activation in the solitary tract nucleus via the vagal afferent pathway.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in regulation of neutrophil chemotaxis	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in centriolar satellite	ISO Inferred from Sequence Orthology more info
located_in cortical cytoskeleton	ISO Inferred from Sequence Orthology more info
located_in membrane	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: 55 kDa erythrocyte membrane protein

Names: membrane palmitoylated protein 1; membrane protein, palmitoylated 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001037659.1 → NP_001032748.1 55 kDa erythrocyte membrane protein

See identical proteins and their annotated locations for NP_001032748.1

Status: PROVISIONAL

Source sequence(s)

AB098073

UniProtKB/TrEMBL

Q5BK33, Q6F6B2

Conserved Domains (4) summary

cd12080
Location:163 → 224

SH3_MPP1; Src Homology 3 domain of Membrane Protein, Palmitoylated 1 (or MAGUK p55 subfamily member 1)

smart00072
Location:292 → 455

GuKc; Guanylate kinase homologues

pfam00595
Location:80 → 150

PDZ; PDZ domain (Also known as DHR or GLGF)

pfam00625
Location:282 → 452

Guanylate_kin; Guanylate kinase