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    Rsph10b radial spoke head 10 homolog B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 288478, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Rsph10bprovided by RGD
    Official Full Name
    radial spoke head 10 homolog Bprovided by RGD
    Primary source
    RGD:1311893
    See related
    EnsemblRapid:ENSRNOG00000001036 AllianceGenome:RGD:1311893
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1311893
    Summary
    Predicted to be located in 9+2 motile cilium. Orthologous to several human genes including RSPH10B (radial spoke head 10 homolog B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 134.1), Lung (RPKM 50.8) and 2 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Rsph10b in Genome Data Viewer
    Location:
    12p11
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (15741097..15788887, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (10627434..10675227, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (12665194..12713834, complement)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene elongation factor 1-gamma-like Neighboring gene oncomodulin Neighboring gene CCZ1 homolog, vacuolar protein trafficking and biogenesis associated Neighboring gene small nucleolar RNA SNORA51 Neighboring gene PMS1 homolog 2, mismatch repair system component Neighboring gene aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 Neighboring gene eukaryotic translation initiation factor 2 alpha kinase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in 9+2 motile cilium ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in axoneme IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    radial spoke head 10 homolog B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013867.1 → NP_001013889.1  radial spoke head 10 homolog B

      See identical proteins and their annotated locations for NP_001013889.1

      Status: PROVISIONAL

      Source sequence(s)
      BC081935
      UniProtKB/Swiss-Prot
      Q66HB5
      Related
      ENSRNOP00000102642.1, ENSRNOT00000159819.1
      Conserved Domains (3) summary
      smart00698
      Location:225 → 244
      MORN; Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases
      COG4642
      Location:122 → 334
      COG4642; Uncharacterized conserved protein [Function unknown]
      pfam02493
      Location:109 → 129
      MORN; MORN repeat

    2. NM_001433437.1 → NP_001420366.1  radial spoke head 10 homolog B

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/Swiss-Prot
      Q66HB5

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      15741097..15788887 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063271137.1 → XP_063127207.1  radial spoke head 10 homolog B isoform X4

    2. XM_006248859.5 → XP_006248921.1  radial spoke head 10 homolog B isoform X1

      See identical proteins and their annotated locations for XP_006248921.1

      Related
      ENSRNOP00000037688.6, ENSRNOT00000034483.8
      Conserved Domains (1) summary
      PLN03185
      Location:158 → 421
      PLN03185; phosphatidylinositol phosphate kinase; Provisional

    3. XM_006248860.5 → XP_006248922.1  radial spoke head 10 homolog B isoform X2

      Conserved Domains (3) summary
      smart00698
      Location:255 → 274
      MORN; Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases
      COG4642
      Location:152 → 364
      COG4642; Uncharacterized conserved protein [Function unknown]
      pfam02493
      Location:140 → 159
      MORN; MORN repeat

    4. XM_006248858.5 → XP_006248920.1  radial spoke head 10 homolog B isoform X1

      See identical proteins and their annotated locations for XP_006248920.1

      Conserved Domains (1) summary
      PLN03185
      Location:158 → 421
      PLN03185; phosphatidylinositol phosphate kinase; Provisional

    5. XM_063271136.1 → XP_063127206.1  radial spoke head 10 homolog B isoform X4

    6. XM_006248861.5 → XP_006248923.1  radial spoke head 10 homolog B isoform X3

      Conserved Domains (3) summary
      smart00698
      Location:225 → 244
      MORN; Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases
      COG4642
      Location:122 → 334
      COG4642; Uncharacterized conserved protein [Function unknown]
      pfam02493
      Location:109 → 129
      MORN; MORN repeat

    7. XM_063271138.1 → XP_063127208.1  radial spoke head 10 homolog B isoform X4

    8. XM_063271135.1 → XP_063127205.1  radial spoke head 10 homolog B isoform X3

      UniProtKB/Swiss-Prot
      Q66HB5

    9. XM_039089176.2 → XP_038945104.1  radial spoke head 10 homolog B isoform X1

      Conserved Domains (1) summary
      PLN03185
      Location:158 → 421
      PLN03185; phosphatidylinositol phosphate kinase; Provisional
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q66HB5.1 GenPept UniProtKB/Swiss-Prot:Q66HB5

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