Gpr62 G protein-coupled receptor 62 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Gpr62provided by RGD
Official Full Name: G protein-coupled receptor 62provided by RGD
Primary source: RGD:1560166
See related: EnsemblRapid:ENSRNOG00000083309 AllianceGenome:RGD:1560166
Gene type: protein coding
RefSeq status: INFERRED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1560166
Summary: Predicted to enable G protein-coupled receptor activity; arrestin family protein binding activity; and identical protein binding activity. Predicted to be involved in ligand-independent adenylate cyclase-activating G protein-coupled receptor signaling pathway and positive regulation of calcium-mediated signaling. Predicted to be part of receptor complex. Predicted to be active in endosome and plasma membrane. Orthologous to human GPR62 (G protein-coupled receptor 62). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: 8q32

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (115981936..115984022, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (107103225..107105311, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (115165655..115170396, complement)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables arrestin family protein binding	ISO Inferred from Sequence Orthology more info
enables identical protein binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in ligand-independent adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of calcium-mediated signaling	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in endosome	IBA Inferred from Biological aspect of Ancestor more info
located_in endosome	ISO Inferred from Sequence Orthology more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info
part_of receptor complex	IBA Inferred from Biological aspect of Ancestor more info
part_of receptor complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: G-protein coupled receptor 62

Names: probable G-protein coupled receptor 62

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001398913.1 → NP_001385842.1 G-protein coupled receptor 62

Status: INFERRED

Source sequence(s)

JAXUCZ010000008

UniProtKB/TrEMBL

D4A2B1

Related

ENSRNOP00000102728.1, ENSRNOT00000138957.1

Conserved Domains (2) summary

cd14964
Location:16 → 42

7tm_GPCRs; TM helix 1 [structural motif]

cl28897
Location:16 → 297

7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily