C1galt1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: C1galt1provided by RGD
Official Full Name: core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1provided by RGD
Primary source: RGD:621105
See related: EnsemblRapid:ENSRNOG00000007804 AllianceGenome:RGD:621105
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity. Predicted to be involved in kidney development. Predicted to act upstream of or within angiogenesis; intestinal epithelial cell development; and protein O-linked glycosylation. Predicted to be located in membrane. Orthologous to human C1GALT1 (core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Kidney (RPKM 303.8), Liver (RPKM 263.2) and 9 other tissues See more
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 4q21

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	4	NC_086022.1 (36894440..36932434)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	4	NC_051339.1 (35930981..35966100)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	4	NC_005103.4 (33890353..33943219)

Chromosome 4 - NC_086022.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity	ISO Inferred from Sequence Orthology more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in angiogenesis	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within angiogenesis	ISO Inferred from Sequence Orthology more info
involved_in angiogenesis	ISO Inferred from Sequence Orthology more info
involved_in intestinal epithelial cell development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within intestinal epithelial cell development	ISO Inferred from Sequence Orthology more info
involved_in kidney development	ISO Inferred from Sequence Orthology more info
involved_in protein O-linked glycosylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein O-linked glycosylation	ISO Inferred from Sequence Orthology more info
involved_in protein glycosylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	ISO Inferred from Sequence Orthology more info

General protein information

Go to the top of the page Help

Preferred Names: glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

Names: core 1 O-glycan T-synthase; core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1; core 1 beta1,3-galactosyltransferase 1; core 1 beta3-Gal-T; core 1 beta3-Gal-T1; core1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase (C1galt1); core1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1; core1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 13-galactosyltransferase (C1galt1)

NP_001385639.1

EC 2.4.1.122

NP_075239.1

EC 2.4.1.122

XP_063142739.1

EC 2.4.1.122

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001398710.1 → NP_001385639.1 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 isoform 1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000004

UniProtKB/TrEMBL

A0A8L2Q5I0

Related

ENSRNOP00000010375.2, ENSRNOT00000010375.4

Conserved Domains (1) summary

cl21608
Location:115 → 256

Galactosyl_T; Galactosyltransferase
NM_022950.3 → NP_075239.1 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 isoform 2

See identical proteins and their annotated locations for NP_075239.1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000004

UniProtKB/Swiss-Prot

Q9JJ05

UniProtKB/TrEMBL

A6IDW5

Conserved Domains (1) summary

cl21608
Location:107 → 248

Galactosyl_T; Galactosyltransferase