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    Abcf3 ATP binding cassette subfamily F member 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287982, updated on 4-Jan-2025

    Summary

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    Official Symbol
    Abcf3provided by RGD
    Official Full Name
    ATP binding cassette subfamily F member 3provided by RGD
    Primary source
    RGD:1310468
    See related
    EnsemblRapid:ENSRNOG00000001710 AllianceGenome:RGD:1310468
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable ATP binding activity. Predicted to be involved in defense response to virus. Orthologous to human ABCF3 (ATP binding cassette subfamily F member 3). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Biased expression in Muscle (RPKM 224.1), Heart (RPKM 222.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Abcf3 in Genome Data Viewer
    Location:
    11q23
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (93844863..93856595, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (80340476..80352211, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (84026206..84037938, complement)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene ALG3, alpha-1,3- mannosyltransferase Neighboring gene microRNA 1224 Neighboring gene von Willebrand factor A domain containing 5B2 Neighboring gene uncharacterized LOC102551647 Neighboring gene uncharacterized LOC102551795 Neighboring gene adaptor related protein complex 2 subunit mu 1 Neighboring gene dishevelled segment polarity protein 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. E-cadherin interactome complexity and robustness resolved by quantitative proteomics. Guo Z, et al. Sci Signal, 2014 Dec 2. PMID 25468996, Free PMC Article
    2. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response to virus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ATP-binding cassette sub-family F member 3
    Names
    ATP-binding cassette, sub-family F (GCN20), member 3
    ATP-binding cassette, subfamily F (GCN20), member 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001011896.1 → NP_001011896.1  ATP-binding cassette sub-family F member 3

      Status: PROVISIONAL

      Source sequence(s)
      BC082042
      UniProtKB/Swiss-Prot
      Q66H39
      UniProtKB/TrEMBL
      A6JSA8
      Related
      ENSRNOP00000109432.1, ENSRNOT00000133139.1
      Conserved Domains (4) summary
      cd03221
      Location:178 → 401
      ABCF_EF-3; ATP-binding cassette domain of elongation factor 3, subfamily F
      PLN03073
      Location:6 → 700
      PLN03073; ABC transporter F family; Provisional
      pfam12848
      Location:395 → 477
      ABC_tran_Xtn; ABC transporter
      cl21455
      Location:266 → 363
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      93844863..93856595 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063270329.1 → XP_063126399.1  ATP-binding cassette sub-family F member 3 isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q66H39.1 GenPept UniProtKB/Swiss-Prot:Q66H39

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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