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    Meig1 meiosis/spermiogenesis associated 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 679834, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Meig1provided by RGD
    Official Full Name
    meiosis/spermiogenesis associated 1provided by RGD
    Primary source
    RGD:1583655
    See related
    EnsemblRapid:ENSRNOG00000016283 AllianceGenome:RGD:1583655
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to act upstream of or within manchette assembly and protein localization. Predicted to be located in cytosol and manchette. Predicted to be active in nucleus. Orthologous to human MEIG1 (meiosis/spermiogenesis associated 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 809.2) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Meig1 in Genome Data Viewer
    Location:
    17q12.3
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (79718630..79737604)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (74810791..74828433)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (78813656..78829411)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120097881 Neighboring gene SUV39H2 histone lysine methyltransferase Neighboring gene DNA cross-link repair 1C Neighboring gene metallothionein 1, pseudogene 3 Neighboring gene uncharacterized LOC120097878 Neighboring gene ribosomal protein L34, pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Haploinsufficiency for the murine orthologue of Chlamydomonas PF20 disrupts spermatogenesis. Zhang Z, et al. Proc Natl Acad Sci U S A, 2004 Aug 31. PMID 15328412, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    acts_upstream_of_or_within manchette assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within protein localization ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of sperm axoneme assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within sperm axoneme assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of spermatogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within spermatogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in manchette ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    meiosis expressed gene 1 protein homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134882.1 → NP_001128354.1  meiosis expressed gene 1 protein homolog

      See identical proteins and their annotated locations for NP_001128354.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      A0A0G2JV95, A6JM18, D4A0V5
      Conserved Domains (1) summary
      pfam15163
      Location:11 → 86
      Meiosis_expr; Meiosis-expressed

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      79718630..79737604
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063276729.1 → XP_063132799.1  meiosis expressed gene 1 protein homolog isoform X1

      UniProtKB/TrEMBL
      A0A0G2JV95, A6JM18, D4A0V5

    2. XM_006254278.5 → XP_006254340.1  meiosis expressed gene 1 protein homolog isoform X1

      See identical proteins and their annotated locations for XP_006254340.1

      UniProtKB/TrEMBL
      A0A0G2JV95, A6JM18, D4A0V5
      Conserved Domains (1) summary
      pfam15163
      Location:11 → 86
      Meiosis_expr; Meiosis-expressed

    3. XM_017600662.3 → XP_017456151.1  meiosis expressed gene 1 protein homolog isoform X1

      UniProtKB/TrEMBL
      A0A0G2JV95, A6JM18, D4A0V5
      Conserved Domains (1) summary
      pfam15163
      Location:11 → 86
      Meiosis_expr; Meiosis-expressed

    4. XM_008771888.4 → XP_008770110.1  meiosis expressed gene 1 protein homolog isoform X1

      See identical proteins and their annotated locations for XP_008770110.1

      UniProtKB/TrEMBL
      A0A0G2JV95, A6JM18, D4A0V5
      Conserved Domains (1) summary
      pfam15163
      Location:11 → 86
      Meiosis_expr; Meiosis-expressed

    5. XM_006254276.4 → XP_006254338.1  meiosis expressed gene 1 protein homolog isoform X1

      See identical proteins and their annotated locations for XP_006254338.1

      UniProtKB/TrEMBL
      A0A0G2JV95, A6JM18, D4A0V5
      Conserved Domains (1) summary
      pfam15163
      Location:11 → 86
      Meiosis_expr; Meiosis-expressed

    6. XM_039096057.1 → XP_038951985.1  meiosis expressed gene 1 protein homolog isoform X1

      UniProtKB/TrEMBL
      A0A0G2JV95, A6JM18, D4A0V5
      Related
      ENSRNOP00000069398.2, ENSRNOT00000090779.3
      Conserved Domains (1) summary
      pfam15163
      Location:11 → 86
      Meiosis_expr; Meiosis-expressed

    7. XM_039096058.2 → XP_038951986.1  meiosis expressed gene 1 protein homolog isoform X1

      UniProtKB/TrEMBL
      A0A0G2JV95, A6JM18, D4A0V5
      Conserved Domains (1) summary
      pfam15163
      Location:11 → 86
      Meiosis_expr; Meiosis-expressed
    Nucleotide Protein Strain
    Heading Accession and Version

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