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    Cd82 Cd82 molecule [ Rattus norvegicus (Norway rat) ]

    Gene ID: 83628, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cd82provided by RGD
    Official Full Name
    Cd82 moleculeprovided by RGD
    Primary source
    RGD:69070
    See related
    EnsemblRapid:ENSRNOG00000000047 AllianceGenome:RGD:69070
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Kai1
    Summary
    Predicted to be located in membrane. Predicted to be active in plasma membrane. Biomarker of hypertension and ovarian cancer. Orthologous to human CD82 (CD82 molecule). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 424.5), Kidney (RPKM 309.3) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Cd82 in Genome Data Viewer
    Location:
    3q31
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (99842748..99887298, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (79387361..79431847, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (82324344..82368846, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120101602 Neighboring gene uncharacterized LOC134486408 Neighboring gene ALX homeobox 4 Neighboring gene exostosin glycosyltransferase 2 Neighboring gene uncharacterized LOC120101603

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in membrane  
    is_active_in plasma membrane  
    located_in plasma membrane  
    located_in plasma membrane  

    General protein information

    Preferred Names
    CD82 antigen
    Names
    CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4))
    Kangai 1 (suppression of tumerigenicity 6 prostate) CD82 antigen
    Kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4))
    kangai 1 (suppression of tumorigenicity 6), prostate
    metastasis suppressor Kangai-1 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001429482.1NP_001416411.1  CD82 antigen

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/Swiss-Prot
      O70352
      UniProtKB/TrEMBL
      A0A8I5ZZR7, A6HNI9, F7EV99, Q6IN14
    2. NM_001429483.1NP_001416412.1  CD82 antigen

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/Swiss-Prot
      O70352
      UniProtKB/TrEMBL
      A0A8I5ZZR7, A6HNI9, F7EV99, Q6IN14
    3. NM_031797.2NP_113985.2  CD82 antigen

      See identical proteins and their annotated locations for NP_113985.2

      Status: PROVISIONAL

      Source sequence(s)
      BC072498
      UniProtKB/Swiss-Prot
      O70352
      UniProtKB/TrEMBL
      A0A8I5ZZR7, A6HNI9, F7EV99, Q6IN14
      Related
      ENSRNOP00000000052.6, ENSRNOT00000000052.6
      Conserved Domains (2) summary
      cd03160
      Location:106228
      CD37_CD82_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD37_CD82_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
      pfam00335
      Location:24255
      Tetraspannin; Tetraspanin family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      99842748..99887298 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006234598.3XP_006234660.1  CD82 antigen isoform X1

      Related
      ENSRNOP00000078723.2, ENSRNOT00000097921.2
      Conserved Domains (2) summary
      cd03160
      Location:106228
      CD37_CD82_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD37_CD82_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
      pfam00335
      Location:24255
      Tetraspannin; Tetraspanin family
    2. XM_006234597.5XP_006234659.1  CD82 antigen isoform X1

      Conserved Domains (2) summary
      cd03160
      Location:106228
      CD37_CD82_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD37_CD82_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
      pfam00335
      Location:24255
      Tetraspannin; Tetraspanin family
    3. XM_039105948.2XP_038961876.1  CD82 antigen isoform X2

      UniProtKB/TrEMBL
      A6HNJ0
      Conserved Domains (1) summary
      cd03160
      Location:40162
      CD37_CD82_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD37_CD82_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
    4. XM_039105951.2XP_038961879.1  CD82 antigen isoform X3

      Conserved Domains (1) summary
      cd03160
      Location:1112
      CD37_CD82_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD37_CD82_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
    5. XM_039105953.2XP_038961881.1  CD82 antigen isoform X3

      Conserved Domains (1) summary
      cd03160
      Location:1112
      CD37_CD82_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD37_CD82_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
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