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    Zfp202 zinc finger protein 202 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500981, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp202provided by RGD
    Official Full Name
    zinc finger protein 202provided by RGD
    Primary source
    RGD:1562294
    See related
    EnsemblRapid:ENSRNOG00000058932 AllianceGenome:RGD:1562294
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1562294
    Summary
    Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in chromosome; nuclear body; and nucleolus. Orthologous to human ZNF202 (zinc finger protein 202). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 94.8), Thymus (RPKM 45.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfp202 in Genome Data Viewer
    Location:
    8q22
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (49439849..49460117)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (40542665..40567397)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (44047586..44068990)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 225 Neighboring gene uncharacterized LOC120094120 Neighboring gene olfactory receptor family 6 subfamily X member 1 Neighboring gene sodium voltage-gated channel beta subunit 3 Neighboring gene GRAM domain containing 1B Neighboring gene uncharacterized LOC134480034

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. A broad role for the zinc finger protein ZNF202 in human lipid metabolism. Wagner S, et al. J Biol Chem, 2000 May 26. PMID 10748193
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in chromosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nuclear body IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 202

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109290.1 → NP_001102760.1  zinc finger protein 202

      See identical proteins and their annotated locations for NP_001102760.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473975
      UniProtKB/TrEMBL
      A6J3P9, D4A7G1
      Conserved Domains (4) summary
      smart00431
      Location:45 → 155
      SCAN; leucine rich region
      smart00349
      Location:239 → 299
      KRAB; krueppel associated box
      COG5048
      Location:334 → 626
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:395 → 415
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      49439849..49460117
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063265964.1 → XP_063122034.1  zinc finger protein 202 isoform X1

      UniProtKB/TrEMBL
      A6J3P9, D4A7G1

    2. XM_039081932.2 → XP_038937860.1  zinc finger protein 202 isoform X1

      UniProtKB/TrEMBL
      A6J3P9, D4A7G1
      Conserved Domains (4) summary
      smart00431
      Location:45 → 155
      SCAN; leucine rich region
      smart00349
      Location:239 → 299
      KRAB; krueppel associated box
      COG5048
      Location:334 → 626
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:395 → 415
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. XM_017595831.3 → XP_017451320.1  zinc finger protein 202 isoform X1

      UniProtKB/TrEMBL
      A6J3P9, D4A7G1
      Conserved Domains (4) summary
      smart00431
      Location:45 → 155
      SCAN; leucine rich region
      smart00349
      Location:239 → 299
      KRAB; krueppel associated box
      COG5048
      Location:334 → 626
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:395 → 415
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_017595828.3 → XP_017451317.1  zinc finger protein 202 isoform X1

      UniProtKB/TrEMBL
      A6J3P9, D4A7G1
      Related
      ENSRNOP00000075094.3, ENSRNOT00000084416.3
      Conserved Domains (4) summary
      smart00431
      Location:45 → 155
      SCAN; leucine rich region
      smart00349
      Location:239 → 299
      KRAB; krueppel associated box
      COG5048
      Location:334 → 626
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:395 → 415
      ZF_C2H2; C2H2 Zn finger [structural motif]

    5. XM_017595832.3 → XP_017451321.1  zinc finger protein 202 isoform X1

      UniProtKB/TrEMBL
      A6J3P9, D4A7G1
      Conserved Domains (4) summary
      smart00431
      Location:45 → 155
      SCAN; leucine rich region
      smart00349
      Location:239 → 299
      KRAB; krueppel associated box
      COG5048
      Location:334 → 626
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:395 → 415
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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