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    Rsrc1 arginine and serine rich coiled-coil 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361956, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rsrc1provided by RGD
    Official Full Name
    arginine and serine rich coiled-coil 1provided by RGD
    Primary source
    RGD:1304968
    See related
    EnsemblRapid:ENSRNOG00000062777 AllianceGenome:RGD:1304968
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    SRrp53; RGD1304968
    Summary
    Predicted to be involved in alternative mRNA splicing, via spliceosome and nucleocytoplasmic transport. Predicted to act upstream of or within RNA splicing; protein phosphorylation; and response to antibiotic. Predicted to be located in nuclear speck. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 70. Orthologous to human RSRC1 (arginine and serine rich coiled-coil 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 55.9), Thymus (RPKM 41.2) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Rsrc1 in Genome Data Viewer
    Location:
    2q31-q32
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (153536839..153942825)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (151226821..151632771)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (164126898..164533652)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120100839 Neighboring gene aminoacyl tRNA synthetase complex-interacting multifunctional protein 1, pseudogene 2 Neighboring gene SHOX homeobox 2 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase-like Neighboring gene uncharacterized LOC134485626 Neighboring gene small nucleolar RNA SNORA44 Neighboring gene myeloid leukemia factor 1 Neighboring gene G elongation factor, mitochondrial 1 Neighboring gene latexin

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA splicing ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in alternative mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in alternative mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within alternative mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mRNA splicing, via spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within nucleocytoplasmic transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in nucleocytoplasmic transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in nucleocytoplasmic transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within response to antibiotic ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear speck ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    serine/Arginine-related protein 53
    Names
    arginine/serine-rich coiled-coil 1
    arginine/serine-rich coiled-coil protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014172.2NP_001014194.1  serine/Arginine-related protein 53

      See identical proteins and their annotated locations for NP_001014194.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/Swiss-Prot
      Q5PPJ2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      153536839..153942825
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063282107.1XP_063138177.1  serine/Arginine-related protein 53 isoform X1

      UniProtKB/Swiss-Prot
      Q5PPJ2
      Related
      ENSRNOP00000096142.1, ENSRNOT00000113236.2
    2. XM_063282106.1XP_063138176.1  serine/Arginine-related protein 53 isoform X1

      UniProtKB/Swiss-Prot
      Q5PPJ2
      Related
      ENSRNOP00000081280.1, ENSRNOT00000101324.2
    3. XM_039102629.2XP_038958557.1  serine/Arginine-related protein 53 isoform X1

      UniProtKB/Swiss-Prot
      Q5PPJ2