Pigy phosphatidylinositol glycan anchor biosynthesis, class Y [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Pigyprovided by RGD
Official Full Name: phosphatidylinositol glycan anchor biosynthesis, class Yprovided by RGD
Primary source: RGD:2318067
See related: EnsemblRapid:ENSRNOG00000052134 AllianceGenome:RGD:2318067
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Pigyl
Summary: Predicted to contribute to phosphatidylinositol N-acetylglucosaminyltransferase activity. Predicted to act upstream of or within GPI anchor biosynthetic process. Predicted to be located in endoplasmic reticulum membrane and plasma membrane. Predicted to be part of glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex. Human ortholog(s) of this gene implicated in hyperphosphatasia with impaired intellectual development syndrome 6. Orthologous to human PIGY (phosphatidylinositol glycan anchor biosynthesis class Y). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Kidney (RPKM 61.9), Adrenal (RPKM 54.9) and 9 other tissues See more
Orthologs: mouse all
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Genomic context

Location:: 8q13

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (28965634..28967876)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (20689621..20691863)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (23167974..23170215)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

RH127336 (e-PCR)
- UniSTS:210646

RH140820 (e-PCR)
- UniSTS:210646

RH128875 (e-PCR)
- UniSTS:212183

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
contributes_to phosphatidylinositol N-acetylglucosaminyltransferase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within GPI anchor biosynthetic process	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum membrane	ISO Inferred from Sequence Orthology more info
part_of glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: phosphatidylinositol N-acetylglucosaminyltransferase subunit Y

Names: rCG31672-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.