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    Cog1 component of oligomeric golgi complex 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 303652, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cog1provided by RGD
    Official Full Name
    component of oligomeric golgi complex 1provided by RGD
    Primary source
    RGD:1304594
    See related
    EnsemblRapid:ENSRNOG00000002795 AllianceGenome:RGD:1304594
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in Golgi organization; glycosylation; and retrograde transport, vesicle recycling within Golgi. Predicted to be located in membrane. Predicted to be part of Golgi transport complex. Predicted to be active in Golgi apparatus. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIg. Orthologous to human COG1 (component of oligomeric golgi complex 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 104.3), Adrenal (RPKM 98.2) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Cog1 in Genome Data Viewer
    Location:
    10q32.1
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (99192604..99207640)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (98695481..98708495)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (102167594..102180569)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 39, member 11 Neighboring gene transfer RNA alanine (anticodon UGC) 10 Neighboring gene somatostatin receptor 2 Neighboring gene VCP nuclear cofactor family member 1 Neighboring gene mitochondrial nucleoid associated protein 1 Neighboring gene cleavage and polyadenylation specific factor 4-like

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in Golgi organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in glycosylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in retrograde transport, vesicle recycling within Golgi ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of Golgi transport complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    conserved oligomeric Golgi complex subunit 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107062.2NP_001100532.2  conserved oligomeric Golgi complex subunit 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      B5DFI1
      Related
      ENSRNOP00000091572.1, ENSRNOT00000113311.2
      Conserved Domains (1) summary
      pfam08700
      Location:1791
      Vps51; Vps51/Vps67

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      99192604..99207640
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063269227.1XP_063125297.1  conserved oligomeric Golgi complex subunit 1 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AFV4, F1LND1

    RNA

    1. XR_005489864.2 RNA Sequence