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    Khnyn KH and NYN domain containing [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498517, updated on 9-Dec-2024

    Summary

    Official Symbol
    Khnynprovided by RGD
    Official Full Name
    KH and NYN domain containingprovided by RGD
    Primary source
    RGD:1565688
    See related
    EnsemblRapid:ENSRNOG00000020506 AllianceGenome:RGD:1565688
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Khnyn-ps1; RGD1565688
    Summary
    Predicted to enable RNA endonuclease activity and mRNA binding activity. Predicted to be active in cytoplasmic ribonucleoprotein granule and nucleus. Orthologous to human KHNYN (KH and NYN domain containing). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 244.8), Spleen (RPKM 192.7) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Khnyn in Genome Data Viewer
    Location:
    15p13
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (33335290..33349553)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (29365399..29379650)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (34551570..34563729)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene NYN domain and retroviral integrase containing Neighboring gene cerebellin 3 precursor Neighboring gene short chain dehydrogenase/reductase family 39U, member 1 Neighboring gene transfer RNA alanine (anticodon AGC) 50 Neighboring gene large ribosomal subunit protein eL21-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA endonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasmic ribonucleoprotein granule IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    protein KHNYN
    Names
    KH and NYN domain containing, pseudogene 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427600.1NP_001414529.1  protein KHNYN

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000015
      UniProtKB/TrEMBL
      D3Z8M3
      Related
      ENSRNOP00000027802.6, ENSRNOT00000027802.8

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      33335290..33349553
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063274550.1XP_063130620.1  protein KHNYN isoform X1

      Related
      ENSRNOP00000107571.1, ENSRNOT00000161868.1
    2. XM_063274551.1XP_063130621.1  protein KHNYN isoform X2

    RNA

    1. XR_010057844.1 RNA Sequence

    2. XR_010057845.1 RNA Sequence

    3. XR_010057847.1 RNA Sequence

    4. XR_010057846.1 RNA Sequence