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    Nxpe3 neurexophilin and PC-esterase domain family, member 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 681096, updated on 9-Dec-2024

    Summary

    Official Symbol
    Nxpe3provided by RGD
    Official Full Name
    neurexophilin and PC-esterase domain family, member 3provided by RGD
    Primary source
    RGD:1584648
    See related
    EnsemblRapid:ENSRNOG00000001608 AllianceGenome:RGD:1584648
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam55c
    Summary
    Orthologous to human NXPE3 (neurexophilin and PC-esterase domain family member 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 91.3), Brain (RPKM 70.1) and 8 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Nxpe3 in Genome Data Viewer
    Location:
    11q12
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (58195951..58246739)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (44726905..44777694)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (47188332..47238372)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L24 Neighboring gene uncharacterized LOC134481067 Neighboring gene centrosomal protein 97 Neighboring gene adaptor related protein complex 3 subunit sigma 1, pseudogene 1 Neighboring gene NFKB inhibitor zeta Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    NXPE family member 3
    Names
    family with sequence similarity 55, member C
    protein FAM55C

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109435.1NP_001102905.1  NXPE family member 3 isoform 1

      See identical proteins and their annotated locations for NP_001102905.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473967
      UniProtKB/TrEMBL
      A6IQR4, D4ACA1
      Related
      ENSRNOP00000104147.1, ENSRNOT00000165302.1
      Conserved Domains (1) summary
      pfam06312
      Location:75284
      Neurexophilin; Neurexophilin
    2. NM_001433918.1NP_001420847.1  NXPE family member 3 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/TrEMBL
      A6IQR4, D4ACA1
    3. NM_001433919.1NP_001420848.1  NXPE family member 3 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/TrEMBL
      A6IQR4, D4ACA1
    4. NM_001433920.1NP_001420849.1  NXPE family member 3 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/TrEMBL
      A0A0G2JYZ2

    RNA

    1. NR_197600.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      58195951..58246739
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006248252.5XP_006248314.1  NXPE family member 3 isoform X1

      Related
      ENSRNOP00000002188.3, ENSRNOT00000002188.7
      Conserved Domains (1) summary
      pfam06312
      Location:75284
      Neurexophilin; Neurexophilin
    2. XM_039088623.2XP_038944551.1  NXPE family member 3 isoform X4

      Conserved Domains (1) summary
      pfam06312
      Location:75275
      Neurexophilin
    3. XM_006248253.5XP_006248315.1  NXPE family member 3 isoform X1

      Conserved Domains (1) summary
      pfam06312
      Location:75284
      Neurexophilin; Neurexophilin
    4. XM_039088621.2XP_038944549.1  NXPE family member 3 isoform X2

      Related
      ENSRNOP00000070847.1, ENSRNOT00000079598.3
      Conserved Domains (1) summary
      pfam06312
      Location:59268
      Neurexophilin
    5. XM_063270764.1XP_063126834.1  NXPE family member 3 isoform X3