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    Tubb6 tubulin, beta 6 class V [ Rattus norvegicus (Norway rat) ]

    Gene ID: 307351, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tubb6provided by RGD
    Official Full Name
    tubulin, beta 6 class Vprovided by RGD
    Primary source
    RGD:1305887
    See related
    EnsemblRapid:ENSRNOG00000018371 AllianceGenome:RGD:1305887
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305887
    Summary
    Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to be located in intercellular bridge and mitotic spindle. Predicted to be active in cytoplasm and microtubule. Orthologous to human TUBB6 (tubulin beta 6 class V). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Uterus (RPKM 136.2), Muscle (RPKM 102.0) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Tubb6 in Genome Data Viewer
    Location:
    18q12.1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (63213287..63222926)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (60943394..60953031)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (63130542..63140181)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134483046 Neighboring gene cell death-inducing DFFA-like effector a Neighboring gene AFG3 like matrix AAA peptidase subunit 2 Neighboring gene uncharacterized LOC134482956 Neighboring gene cytochrome b-c1 complex subunit 7-like Neighboring gene PRELI domain containing 3A

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    General gene information

    Clone Names

    • MGC116110

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables GTPase activity  
    Component Evidence Code Pubs
    located_in intercellular bridge  
    located_in intercellular bridge  
    located_in microtubule  
    located_in microtubule cytoskeleton  
    located_in mitotic spindle  
    located_in mitotic spindle  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025675.1NP_001020846.1  tubulin beta-6 chain

      See identical proteins and their annotated locations for NP_001020846.1

      Status: PROVISIONAL

      Source sequence(s)
      BC097977
      UniProtKB/TrEMBL
      A0A8I5ZT08, A6IXU7, F7FF15, Q4QQV0
      Related
      ENSRNOP00000081460.2, ENSRNOT00000107745.2
      Conserved Domains (1) summary
      PLN00220
      Location:1431
      PLN00220; tubulin beta chain; Provisional

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      63213287..63222926
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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