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    Ints10 integrator complex subunit 10 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 290679, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ints10provided by RGD
    Official Full Name
    integrator complex subunit 10provided by RGD
    Primary source
    RGD:1304711
    See related
    EnsemblRapid:ENSRNOG00000055331 AllianceGenome:RGD:1304711
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1304711
    Summary
    Predicted to be involved in snRNA processing. Predicted to be located in nucleus. Predicted to be part of integrator complex. Orthologous to human INTS10 (integrator complex subunit 10). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 148.3), Brain (RPKM 111.7) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Ints10 in Genome Data Viewer
    Location:
    16p14
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (25682818..25735840, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (20915223..20947146, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (22616480..22647315, complement)

    Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene lipoprotein lipase Neighboring gene uncharacterized LOC134482365 Neighboring gene ribosomal protein L10, pseudogene 7 Neighboring gene chondroitin sulfate N-acetylgalactosaminyltransferase 1 Neighboring gene splicing factor YJU2-like Neighboring gene uncharacterized LOC120097455

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in snRNA processing  
    involved_in snRNA processing  
    Component Evidence Code Pubs
    part_of integrator complex  
    part_of integrator complex  
    is_active_in nucleus  
    located_in nucleus  

    General protein information

    Preferred Names
    integrator complex subunit 10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134416.2NP_001127888.1  integrator complex subunit 10

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000016
      UniProtKB/TrEMBL
      B2RYP7
      Related
      ENSRNOP00000074576.3, ENSRNOT00000091335.3
    2. NM_001428697.1NP_001415626.1  integrator complex subunit 10

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000016
      UniProtKB/TrEMBL
      B2RYP7

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086034.1 Reference GRCr8

      Range
      25682818..25735840 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063275210.1XP_063131280.1  integrator complex subunit 10 isoform X8

      UniProtKB/TrEMBL
      A0A0G2K8E5
      Related
      ENSRNOP00000093524.2, ENSRNOT00000106088.2
    2. XM_039094352.2XP_038950280.1  integrator complex subunit 10 isoform X5

      UniProtKB/TrEMBL
      B2RYP7
    3. XM_039094353.2XP_038950281.1  integrator complex subunit 10 isoform X6

      UniProtKB/TrEMBL
      B2RYP7
      Related
      ENSRNOP00000104397.1, ENSRNOT00000147726.1
    4. XM_039094349.2XP_038950277.1  integrator complex subunit 10 isoform X2

      UniProtKB/TrEMBL
      B2RYP7
      Related
      ENSRNOP00000112411.1, ENSRNOT00000135558.1
    5. XM_039094355.2XP_038950283.1  integrator complex subunit 10 isoform X7

      UniProtKB/TrEMBL
      B2RYP7
      Related
      ENSRNOP00000075205.3, ENSRNOT00000087027.3
    6. XM_039094350.2XP_038950278.1  integrator complex subunit 10 isoform X3

      UniProtKB/TrEMBL
      B2RYP7
      Related
      ENSRNOP00000105336.1, ENSRNOT00000132293.1
    7. XM_039094351.2XP_038950279.1  integrator complex subunit 10 isoform X4

      UniProtKB/TrEMBL
      B2RYP7
    8. XM_039094348.2XP_038950276.1  integrator complex subunit 10 isoform X1

      UniProtKB/TrEMBL
      B2RYP7
    9. XM_039094357.2XP_038950285.1  integrator complex subunit 10 isoform X10

      UniProtKB/TrEMBL
      A6KFJ1
    10. XM_063275212.1XP_063131282.1  integrator complex subunit 10 isoform X9

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