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    Emcn endomucin [ Rattus norvegicus (Norway rat) ]

    Gene ID: 295490, updated on 9-Dec-2024

    Summary

    Official Symbol
    Emcnprovided by RGD
    Official Full Name
    endomucinprovided by RGD
    Primary source
    RGD:1303218
    See related
    EnsemblRapid:ENSRNOG00000022910 AllianceGenome:RGD:1303218
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable carbohydrate binding activity. Predicted to be involved in angiogenesis; cell-cell adhesion; and regulation of cell adhesion. Predicted to act upstream of or within hematopoietic stem cell homeostasis. Predicted to be located in plasma membrane. Orthologous to human EMCN (endomucin). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 509.8), Kidney (RPKM 368.8) and 8 other tissues See more
    Orthologs
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    Genomic context

    See Emcn in Genome Data Viewer
    Location:
    2q43
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (228564445..228644370)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (225891100..225970932)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (242634319..242715489)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene protein kinase C and casein kinase substrate in neurons 3, pseudogene 1 Neighboring gene uncharacterized LOC120100622 Neighboring gene uncharacterized LOC120100949 Neighboring gene uncharacterized LOC134485976 Neighboring gene DNA-damage-inducible transcript 4-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Clone Names

    • MGC94175

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables carbohydrate binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables carbohydrate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in angiogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in angiogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in angiogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cell-cell adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell-cell adhesion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within hematopoietic stem cell homeostasis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of cell adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of cell adhesion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004228.1NP_001004228.1  endomucin precursor

      See identical proteins and their annotated locations for NP_001004228.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079155
      UniProtKB/Swiss-Prot
      Q6AY82
      UniProtKB/TrEMBL
      A6HW00
      Related
      ENSRNOP00000109793.1, ENSRNOT00000142209.1
      Conserved Domains (1) summary
      pfam07010
      Location:1250
      Endomucin; Endomucin

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      228564445..228644370
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063281668.1XP_063137738.1  endomucin isoform X1

      UniProtKB/TrEMBL
      A6HW00
      Related
      ENSRNOP00000033031.4, ENSRNOT00000035700.5
    2. XM_063281669.1XP_063137739.1  endomucin isoform X2

      UniProtKB/TrEMBL
      A6HW01
      Related
      ENSRNOP00000099736.1, ENSRNOT00000125911.1