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    Tm2d3 TM2 domain containing 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 292995, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tm2d3provided by RGD
    Official Full Name
    TM2 domain containing 3provided by RGD
    Primary source
    RGD:1564929
    See related
    EnsemblRapid:ENSRNOG00000011290 AllianceGenome:RGD:1564929
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1564929
    Summary
    Predicted to be involved in lateral inhibition. Predicted to be located in membrane. Orthologous to human TM2D3 (TM2 domain containing 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 59.5), Heart (RPKM 50.6) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Tm2d3 in Genome Data Viewer
    Location:
    1q22
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (128677680..128687580)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (119267194..119277094)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (126573474..126595778)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120099841 Neighboring gene threonyl-tRNA synthetase 3 Neighboring gene uncharacterized LOC108349586 Neighboring gene uncharacterized LOC120099842 Neighboring gene CWC15 spliceosome-associated protein, pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    TM2 domain-containing protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106267.2NP_001099737.1  TM2 domain-containing protein 3 isoform 1

      See identical proteins and their annotated locations for NP_001099737.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I6ACD9, A6JBN3
      Related
      ENSRNOP00000091784.1, ENSRNOT00000094329.2
      Conserved Domains (1) summary
      pfam05154
      Location:196245
      TM2; TM2 domain
    2. NM_001419455.1NP_001406384.1  TM2 domain-containing protein 3 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
    3. NM_001419456.1NP_001406385.1  TM2 domain-containing protein 3 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
    4. NM_001419457.1NP_001406386.1  TM2 domain-containing protein 3 isoform 4

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A6JBN4, D3ZQU1
      Related
      ENSRNOP00000015287.8, ENSRNOT00000015287.9
    5. NM_001419458.1NP_001406387.1  TM2 domain-containing protein 3 isoform 5

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      128677680..128687580
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)