Tsc22d4 TSC22 domain family, member 4 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Tsc22d4provided by RGD
Full Name: TSC22 domain family, member 4provided by RGD
Primary source: RGD:1584380
See related: EnsemblRapid:ENSRNOG00000050805 AllianceGenome:RGD:1584380
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Tilz2; Spacdr; thg-1pit
Summary: Predicted to be involved in several processes, including glucose homeostasis; negative regulation of transcription by RNA polymerase II; and neuron projection extension. Predicted to be located in several cellular components, including dendrite; nucleus; and synapse. Orthologous to human TSC22D4 (TSC22 domain family member 4). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Heart (RPKM 264.0), Thymus (RPKM 115.8) and 8 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 12q12

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	12	NC_086030.1 (24575948..24588806, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	12	NC_051347.1 (18939150..18952008, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	12	NC_005111.4 (22008956..22021814, complement)

Chromosome 12 - NC_086030.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH136799 (e-PCR)
- UniSTS:218888

RH133351 (e-PCR)
- UniSTS:216634

RH143037 (e-PCR)
- UniSTS:232284

RH142348 (e-PCR)
- UniSTS:231595

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in glucose homeostasis	ISO Inferred from Sequence Orthology more info
involved_in glucose homeostasis	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of transcription by RNA polymerase II	ISS Inferred from Sequence or Structural Similarity more info
involved_in neuron cellular homeostasis	ISO Inferred from Sequence Orthology more info
involved_in neuron cellular homeostasis	ISS Inferred from Sequence or Structural Similarity more info
involved_in neuron projection extension	ISO Inferred from Sequence Orthology more info
involved_in neuron projection extension	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
involved_in response to osmotic stress	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within response to osmotic stress	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
located_in dendrite	ISO Inferred from Sequence Orthology more info
located_in dendrite	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info
located_in synapse	ISO Inferred from Sequence Orthology more info
located_in synapse	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: TSC22 domain family protein 4

Names: TSC22-related-inducible leucine zipper protein 2; sperm acrosome developmental regulator; uncharacterized protein C7orf61 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.