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    Ndufb11 NADH:ubiquinone oxidoreductase subunit B11 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 299310, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ndufb11provided by RGD
    Official Full Name
    NADH:ubiquinone oxidoreductase subunit B11provided by RGD
    Primary source
    RGD:1563698
    See related
    EnsemblRapid:ENSRNOG00000008329 AllianceGenome:RGD:1563698
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1563698
    Summary
    Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex I. Human ortholog(s) of this gene implicated in linear skin defects with multiple congenital anomalies 3 and nuclear type mitochondrial complex I deficiency 30. Orthologous to human NDUFB11 (NADH:ubiquinone oxidoreductase subunit B11). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 1195.3), Muscle (RPKM 904.3) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Ndufb11 in Genome Data Viewer
    Location:
    Xq11
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (4126317..4128575)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (1572805..1575063)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (1787266..1789524)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene ubiquitin-like modifier activating enzyme 1 Neighboring gene RNA binding motif protein 10 Neighboring gene U2 spliceosomal RNA Neighboring gene forkhead box N3, pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial
    Names
    NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106756.1NP_001100226.1  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

      See identical proteins and their annotated locations for NP_001100226.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474009
      UniProtKB/TrEMBL
      A0A8I6AUJ7, A6JZT7, D4A7L4
      Related
      ENSRNOP00000011183.4, ENSRNOT00000011183.6
      Conserved Domains (1) summary
      pfam10183
      Location:22139
      ESSS; ESSS subunit of NADH:ubiquinone oxidoreductase (complex I)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      4126317..4128575
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)