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    Rcbtb1 RCC1 and BTB domain containing protein 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361050, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Rcbtb1provided by RGD
    Official Full Name
    RCC1 and BTB domain containing protein 1provided by RGD
    Primary source
    RGD:1308467
    See related
    EnsemblRapid:ENSRNOG00000021712 AllianceGenome:RGD:1308467
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be active in cytoplasm. Orthologous to human RCBTB1 (RCC1 and BTB domain containing protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 205.1), Thymus (RPKM 153.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Rcbtb1 in Genome Data Viewer
    Location:
    15p12
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (37430453..37477920)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (33319586..33362421)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (39622572..39665335)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102551924 Neighboring gene RGD1563302 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC120096998 Neighboring gene ribosomal protein L6, pseudogene 5 Neighboring gene PHD finger protein 11B Neighboring gene PHD finger protein 11-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, et al. J Proteome Res, 2012 Sep 7. PMID 22871113, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    RCC1 and BTB domain-containing protein 1
    Names
    regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108380.3 → NP_001101850.1  RCC1 and BTB domain-containing protein 1

      See identical proteins and their annotated locations for NP_001101850.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000015
      UniProtKB/TrEMBL
      A0A8I5ZM64, A6KHE8
      Related
      ENSRNOP00000079053.1, ENSRNOT00000120010.2
      Conserved Domains (4) summary
      COG5184
      Location:91 → 363
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd18353
      Location:350 → 466
      BTB_POZ_RCBTB1_CLLD7; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in RCC1 and BTB domain-containing protein 1 (RCBTB1)
      cd18528
      Location:466 → 531
      BACK_RCBTB1; BACK (BTB and C-terminal Kelch) domain found in RCC1 and BTB domain-containing protein 1 (RCBTB1)
      pfam00415
      Location:42 → 89
      RCC1; Regulator of chromosome condensation (RCC1) repeat

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      37430453..37477920
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039093499.2 → XP_038949427.1  RCC1 and BTB domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZM64, A6KHE8
      Conserved Domains (4) summary
      COG5184
      Location:91 → 363
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd18353
      Location:350 → 466
      BTB_POZ_RCBTB1_CLLD7; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in RCC1 and BTB domain-containing protein 1 (RCBTB1)
      cd18528
      Location:466 → 531
      BACK_RCBTB1; BACK (BTB and C-terminal Kelch) domain found in RCC1 and BTB domain-containing protein 1 (RCBTB1)
      pfam00415
      Location:42 → 89
      RCC1; Regulator of chromosome condensation (RCC1) repeat

    2. XM_039093498.2 → XP_038949426.1  RCC1 and BTB domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZM64, A6KHE8
      Conserved Domains (4) summary
      COG5184
      Location:91 → 363
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd18353
      Location:350 → 466
      BTB_POZ_RCBTB1_CLLD7; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in RCC1 and BTB domain-containing protein 1 (RCBTB1)
      cd18528
      Location:466 → 531
      BACK_RCBTB1; BACK (BTB and C-terminal Kelch) domain found in RCC1 and BTB domain-containing protein 1 (RCBTB1)
      pfam00415
      Location:42 → 89
      RCC1; Regulator of chromosome condensation (RCC1) repeat

    3. XM_039093500.2 → XP_038949428.1  RCC1 and BTB domain-containing protein 1 isoform X2

      Related
      ENSRNOP00000105754.1, ENSRNOT00000146787.1
      Conserved Domains (4) summary
      COG5184
      Location:91 → 363
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd18353
      Location:350 → 466
      BTB_POZ_RCBTB1_CLLD7; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in RCC1 and BTB domain-containing protein 1 (RCBTB1)
      pfam00415
      Location:42 → 89
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      cl28903
      Location:466 → 510
      BACK; BACK (BTB and C-terminal Kelch) domain

    RNA

    1. XR_010057839.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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