Ftx FTX transcript, XIST regulator [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ftxprovided by RGD
Official Full Name: FTX transcript, XIST regulatorprovided by RGD
Primary source: RGD:1564124
See related: AllianceGenome:RGD:1564124
Gene type: ncRNA
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1564124
Summary: Predicted to act upstream of or within positive regulation of gene expression via chromosomal CpG island demethylation and random inactivation of X chromosome. Orthologous to human FTX (FTX transcript, XIST regulator). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Brain (RPKM 50.9), Adrenal (RPKM 41.2) and 9 other tissues See more
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: Xq22

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	X	NC_086039.1 (72654112..72696097, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	X	NC_051356.1 (68588349..68630338, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	X	NC_005120.4 (74440265..74484164, complement)

Chromosome X - NC_086039.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

LncRNA FTX ameliorates neuropathic pain by targeting miR-320a in a rat model of chronic constriction injury.
Title: LncRNA FTX ameliorates neuropathic pain by targeting miR-320a in a rat model of chronic constriction injury.
LncRNA FTX Involves in the Nogo-66-Induced Inhibition of Neurite Outgrowth Through Regulating PDK1/PKB/GSK-3beta Pathway.
Title: LncRNA FTX Involves in the Nogo-66-Induced Inhibition of Neurite Outgrowth Through Regulating PDK1/PKB/GSK-3β Pathway.
demonstrated the anti-apoptosis ability of FTX during epileptogenesis and uncovered a novel FTX-mediated mechanism in status epilepticus-induced neural apoptosis by targeting miR-21-5p/SOX7 axis, which provides a new target in developing lncRNA-based strategies to reduce SE-induced hippocampal neuron apoptosis
Title: LncRNA FTX inhibits hippocampal neuron apoptosis by regulating miR-21-5p/SOX7 axis in a rat model of temporal lobe epilepsy.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

BF390019 (e-PCR)
- UniSTS:249362

BG377529 (e-PCR)
- UniSTS:244510

RH144297 (e-PCR)
- UniSTS:233542

BE113212 (e-PCR)
- UniSTS:246638

AA892682 (e-PCR)
- UniSTS:250053

RH141217 (e-PCR)
- UniSTS:223213

Other Names

Ftx transcript, Xist regulator (non-protein coding)

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
acts_upstream_of_or_within chromatin organization	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of gene expression via chromosomal CpG island demethylation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within random inactivation of X chromosome	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within regulation of gene expression	ISO Inferred from Sequence Orthology more info

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.