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    Cgm4 carcinoembryonic antigen gene family 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 24257, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cgm4provided by RGD
    Official Full Name
    carcinoembryonic antigen gene family 4provided by RGD
    Primary source
    RGD:1307652
    See related
    EnsemblRapid:ENSRNOG00000062787 AllianceGenome:RGD:1307652
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Cea; CEA4; CEA5; Cear; Psg16; CGM4AA
    Summary
    Predicted to enable protein tyrosine kinase binding activity. Predicted to be involved in regulation of immune system process and signal transduction. Predicted to be active in cell surface and plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 1.9) See more
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    Genomic context

    See Cgm4 in Genome Data Viewer
    Location:
    1q21
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (86904526..86917487)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (77776447..77789408)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (79030291..79043259)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene protein phosphatase 5, catalytic subunit Neighboring gene hypoxia inducible factor 3 subunit alpha Neighboring gene pregnancy specific glycoprotein 16 Neighboring gene CEA cell adhesion molecule 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables protein tyrosine kinase binding  
    Process Evidence Code Pubs
    involved_in regulation of immune system process  
    involved_in signal transduction  
    Component Evidence Code Pubs
    is_active_in cell surface  
    is_active_in plasma membrane  

    General protein information

    Preferred Names
    carcinoembryonic antigen gene family 4

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_012525.1 → NP_036657.1  carcinoembryonic antigen gene family 4 precursor

      See identical proteins and their annotated locations for NP_036657.1

      Status: VALIDATED

      Source sequence(s)
      AA818022, BI283810, BI285964, CB706316, CB766157, CB786391, CB804911, CV118170
      UniProtKB/TrEMBL
      Q4V8J0
      Related
      ENSRNOP00000033854.4, ENSRNOT00000037086.8
      Conserved Domains (3) summary
      cd05774
      Location:157 → 261
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      smart00410
      Location:396 → 473
      IG_like; Immunoglobulin like
      cl11960
      Location:383 → 473
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      86904526..86917487
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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