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    Papolg poly(A) polymerase gamma [ Rattus norvegicus (Norway rat) ]

    Gene ID: 305586, updated on 9-Dec-2024

    Summary

    Official Symbol
    Papolgprovided by RGD
    Official Full Name
    poly(A) polymerase gammaprovided by RGD
    Primary source
    RGD:1310337
    See related
    EnsemblRapid:ENSRNOG00000006261 AllianceGenome:RGD:1310337
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable metal ion binding activity and poly(A) RNA polymerase activity. Predicted to be involved in RNA 3'-end processing and mRNA processing. Predicted to be located in cytosol and nuclear body. Predicted to be active in nucleus. Orthologous to human PAPOLG (poly(A) polymerase gamma). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 114.1), Spleen (RPKM 83.8) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Papolg in Genome Data Viewer
    Location:
    14q22
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (102028842..102062155, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (97827712..97861024, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (108624359..108658371, complement)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120096697 Neighboring gene 60S ribosomal protein L17 pseudogene Neighboring gene uncharacterized LOC134481803 Neighboring gene BCL11 transcription factor A Neighboring gene uncharacterized LOC102557119

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding  
    enables RNA binding  
    enables metal ion binding  
    enables poly(A) RNA polymerase activity  
    enables poly(A) RNA polymerase activity  
    Process Evidence Code Pubs
    involved_in RNA 3'-end processing  
    involved_in biological_process  
    involved_in mRNA processing  
    Component Evidence Code Pubs
    located_in cytosol  
    located_in cytosol  
    located_in nuclear body  
    located_in nuclear body  
    located_in nucleoplasm  
    is_active_in nucleus  
    located_in nucleus  

    General protein information

    Preferred Names
    poly(A) polymerase gamma
    NP_001100714.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107244.1NP_001100714.1  poly(A) polymerase gamma

      See identical proteins and their annotated locations for NP_001100714.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473996
      UniProtKB/TrEMBL
      A6JQ80, D3ZAN6
      Related
      ENSRNOP00000008919.5, ENSRNOT00000008919.7
      Conserved Domains (4) summary
      PRK04654
      Location:489632
      PRK04654; sec-independent translocase; Provisional
      PTZ00418
      Location:3560
      PTZ00418; Poly(A) polymerase; Provisional
      pfam04926
      Location:365504
      PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain
      pfam04928
      Location:20363
      PAP_central; Poly(A) polymerase central domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      102028842..102062155 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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