Bicdl1 BICD family like cargo adaptor 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Bicdl1provided by RGD
Official Full Name: BICD family like cargo adaptor 1provided by RGD
Primary source: RGD:1310292
See related: EnsemblRapid:ENSRNOG00000056955 AllianceGenome:RGD:1310292
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Ccdc64; RGD1310292
Summary: Predicted to enable dynactin binding activity and small GTPase binding activity. Predicted to be involved in Golgi to secretory granule transport; neuron projection development; and vesicle transport along microtubule. Predicted to be located in centrosome. Orthologous to human BICDL1 (BICD family like cargo adaptor 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 77.2), Brain (RPKM 76.3) and 8 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 12q16

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	12	NC_086030.1 (46537525..46626876)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	12	NC_051347.1 (40878190..41001152)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	12	NC_005111.4 (46615597..46703287)

Chromosome 12 - NC_086030.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH140398 (e-PCR)
- UniSTS:222473

RH131047 (e-PCR)
- UniSTS:214330

RH144446 (e-PCR)
- UniSTS:233691

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables dynactin binding	ISO Inferred from Sequence Orthology more info
enables small GTPase binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in Golgi to secretory granule transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in Golgi to secretory granule transport	ISO Inferred from Sequence Orthology more info
involved_in neuron projection development	ISO Inferred from Sequence Orthology more info
involved_in vesicle transport along microtubule	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in centrosome	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: BICD family-like cargo adapter 1

Names: bicaudal D-related protein 1; coiled-coil domain containing 64

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001191667.2 → NP_001178596.1 BICD family-like cargo adapter 1

Status: PROVISIONAL

Source sequence(s)

JAXUCZ010000012

UniProtKB/TrEMBL

A0A8I6GEA9, A6J1S4

Related

ENSRNOP00000110168.1, ENSRNOT00000140704.1

Conserved Domains (2) summary

pfam01665
Location:100 → 240

Rota_NSP3; Rotavirus non-structural protein NSP3

pfam14988
Location:121 → 297

DUF4515; Domain of unknown function (DUF4515)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086030.1 Reference GRCr8

Range

46537525..46626876

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_008769234.4 → XP_008767456.1 BICD family-like cargo adapter 1 isoform X1

UniProtKB/TrEMBL

A0A0G2JY46, A0A0G2KAQ3

Related

ENSRNOP00000075484.2, ENSRNOT00000089494.3

Conserved Domains (2) summary

pfam01665
Location:100 → 240

Rota_NSP3; Rotavirus non-structural protein NSP3

pfam14988
Location:121 → 297

DUF4515; Domain of unknown function (DUF4515)
XM_063271347.1 → XP_063127417.1 BICD family-like cargo adapter 1 isoform X2

UniProtKB/TrEMBL

A0A0G2JY46

Related

ENSRNOP00000109382.1, ENSRNOT00000164424.1
XM_063271348.1 → XP_063127418.1 BICD family-like cargo adapter 1 isoform X3